Responses to Rabies Vaccine in Adults With or Without Antibiotics

PHASE4CompletedINTERVENTIONAL
Enrollment

37

Participants

Timeline

Start Date

July 5, 2018

Primary Completion Date

June 2, 2022

Study Completion Date

June 2, 2022

Conditions
Rabies Human
Interventions
BIOLOGICAL

Rabies Vaccine

A 1.0 milliliter (mL) dose of Imovax® will be given to participants on Day 0 and Day 28 of the study.

DRUG

Metronidazole

The antibiotic regimen will be given for five days beginning 3 days prior to vaccination, on the vaccination day, and one day after vaccination for a total for 5. The regimen will include 500 milligrams (mg) of Flagyl taken by mouth three times a day.

DRUG

Vancomycin

The antibiotic regimen will be given for five days beginning 3 days prior to vaccination, on the vaccination day, and one day after vaccination for a total for 5. The regimen will include 125 mg of Vancocin taken by mouth four times a day.

DRUG

Neomycin Sulfate

The antibiotic regimen will be given for five days beginning 3 days prior to vaccination, on the vaccination day, and one day after vaccination for a total for 5. The regimen will include 500 milligrams (mg) of Neomycin sulfate taken by mouth three times a day.

Trial Locations (2)

30030

The Hope Clinic of the Emory Vaccine Center, Decatur

30322

Winship Cancer Institute of Emory University, Atlanta

All Listed Sponsors
lead

Emory University

OTHER

NCT03557008 - Responses to Rabies Vaccine in Adults With or Without Antibiotics | Biotech Hunter | Biotech Hunter