Hydroxyapatite-toothpaste and Enamel Caries in the Primary Dentition

NACompletedINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

March 1, 2018

Primary Completion Date

December 31, 2019

Study Completion Date

December 31, 2019

Conditions
Tooth DecayHydroxyapatiteTooth DemineralizationTooth Diseases
Interventions
PROCEDURE

Prophylactic

Tooth Brushing HA 3x daily repeated cleaning of all teeth using a standardized electric tooth brush and a non-fluoridated tooth paste containing microcrystalline hydroxylapatite.

PROCEDURE

Cleaning teeth

Tooth Brushing F 3x daily repeated cleaning of all teeth using a standardized electric tooth brush and a fluoridated tooth paste.

DEVICE

Restorative dentistry

If in a subject a significant increase of carious lesions will be observed, her/his parents are informed about the necessity for further caries preventive measures (e.g. dietary changes, use of fluoride products, reduction of cariogenic microflora with chlorhexidine, xylitol chewing gum, etc.) and caries preventive treatment (removing caries and placing a restoration) by the study centers is offered.

Trial Locations (1)

Unknown

Poznan University of Medical Sciences, Department of Integrated Dentistry, Poznan

All Listed Sponsors
collaborator

Medical University of Bialystok

OTHER

collaborator

Wuerzburg University Hospital

OTHER

collaborator

Poznan University of Medical Sciences

OTHER

lead

Dr. Kurt Wolff GmbH & Co. KG

INDUSTRY

NCT03553966 - Hydroxyapatite-toothpaste and Enamel Caries in the Primary Dentition | Biotech Hunter | Biotech Hunter