NCT03552705View on ClinicalTrials.gov

The Effects of Tranexamic Acid on Joint Inflammation and Cartilage Health in Anterior Cruciate Ligament Injured Patients

PHASE2RecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

August 1, 2019

Primary Completion Date

January 14, 2026

Study Completion Date

January 14, 2026

Conditions
Anterior Cruciate Ligament Reconstruction
Interventions
DRUG

Tranexamic Acid

5-day course of oral standard adult oral tranexamic acid dosage of 1300 mg taken 3 times a day (3900 mg/day) and intravenous tranexamic acid during ACL reconstruction surgery (1 gram of iv TXA just prior to incision and 1 gram of iv TXA just prior to wound closure)

DRUG

Placebos

5-day course of oral placebo and intravenous saline during ACL reconstruction surgery

Trial Locations (1)

94305

RECRUITING

Stanford University, Stanford

All Listed Sponsors
collaborator

United States Department of Defense

FED

lead

Stanford University

OTHER