Evaluation of Early CRRT InTerventions in Patients With ECMO(ELITE)

PHASE4CompletedINTERVENTIONAL
Enrollment

131

Participants

Timeline

Start Date

December 18, 2018

Primary Completion Date

October 22, 2022

Study Completion Date

May 1, 2023

Conditions
Cardiogenic Shock
Interventions
DEVICE

Simultaneous CRRT

The patients in the simultaneous CRRT group will receive CRRT within 24 hours after the initiation of ECMO support.

DEVICE

Conventional-indication CRRT

The patients in the conventional-indication group will not receive CRRT until the patient demonstrates AKI and fulfills any one of the criteria of the conventional CRRT indication.

DRUG

Esmolol

The patients in esmolol group will receive a continuous esmolol infusion in addition to the standard care.

DRUG

Standard care

The patients in control group will not receive any beta-blockers, including esmolol, unless the doctor thinks there's a strong indication.

Trial Locations (1)

100029

Beijing Anzhen Hospital, Beijing

All Listed Sponsors
collaborator

The First Affiliated Hospital of Zhengzhou University

OTHER

lead

Beijing Anzhen Hospital

OTHER

NCT03549923 - Evaluation of Early CRRT InTerventions in Patients With ECMO(ELITE) | Biotech Hunter | Biotech Hunter