The Heart & Mind Study

NACompletedINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

November 15, 2018

Primary Completion Date

March 21, 2020

Study Completion Date

March 21, 2020

Conditions
HypertensionCognitive DeclineVascular Cognitive Impairment
Interventions
BEHAVIORAL

High-intensity Interval Training (HIT)

Following the mind-motor training component, participants in the experimental group will then continue in the 45-minute HIT intervention, which will be composed by a 10-minute warm-up, a 25-minute core activity, and a 10-minute cool down. The 25-minute core activity will be carried out based on a 4 x 4 minutes aerobic interval training model. The intensity in each cycle will be prescribed at an individual level, and training heart rates will be determined via a sub-maximal excise testing at baseline and monitored during exercise using a wrist-based heart rate monitor (Suunto). In order to ensure progression in aerobic training over the 6-month intervention, training heart rates will be recalculated at the intervention midpoint (i.e., 3 months), where a new sub-maximal exercise test will be performed. Participants will exercise 60 minutes/day, 3 days/week for 6 months.

BEHAVIORAL

Moderate-intensity Continuous Training (MCT)

After the mind-motor training component, participants in the comparison/control group will then continue in the 45-min MCT intervention, which will be composed by a 10-minute warm-up a 25-minute moderate-intensity continuous aerobic exercise training, and a 10-minute cool down. The exercise intensity will be prescribed at an individual level, and training heart rates will be determined via a sub-maximal excise testing at baseline and monitored during exercise using a wrist-based heart rate monitor (Suunto). In order to ensure progression in aerobic training over the 6-month intervention, training heart rates will be recalculated at the intervention midpoint (i.e., 3 months), where a new sub-maximal exercise test will be performed. Participants will exercise 60 minutes/day, 3 days/week for 6 months.

Trial Locations (1)

N6G 2M1

Western University, Western Centre for Public Health and Family Medicine, London

All Listed Sponsors
lead

Western University, Canada

OTHER

NCT03545958 - The Heart & Mind Study | Biotech Hunter | Biotech Hunter