Impact of Iron Deficiency and Its Correction on Mitochondrial Metabolism of the Cardiomyocyte (MitoCardioFer)

NACompletedINTERVENTIONAL
Enrollment

55

Participants

Timeline

Start Date

January 23, 2019

Primary Completion Date

September 7, 2020

Study Completion Date

September 7, 2020

Conditions
Iron-deficiencyValvular Heart Disease
Interventions
PROCEDURE

myocardial biopsy

Myocardial biopsy (after opening cardiac cavities under general anesthesia for valvular surgery) for mitochondrial metabolism analyses.

PROCEDURE

sternal bone marrow biopsy

Sternal bone marrow biopsy (after sternal opening under general anesthesia for valvular surgery) for the quantification of iron stores

BIOLOGICAL

blood sample

blood sample (under general anesthesia for valvular surgery, using the arterial catheter already in place) for hepcidin quantification (hormone not dosed in the usual martial assessment)

Trial Locations (1)

49100

CHU Angers - DEPARTEMENT D'ANESTHESIE REANIMATION, Angers

All Listed Sponsors
lead

University Hospital, Angers

OTHER_GOV

NCT03541213 - Impact of Iron Deficiency and Its Correction on Mitochondrial Metabolism of the Cardiomyocyte (MitoCardioFer) | Biotech Hunter | Biotech Hunter