A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its Safety

Hospital Erasme - Cardiology department, Brussels

Gottsegen György Országos Kardiológiai Intézet, Budapest

Clinique Universitaires de Saint Luc, Departement cardio-vasculaires intensives, Brussels

Westmead Hospital Department of Renal Medicine, Sydney

Renal Research, Gosford

Baker Heart and Diabetes Institute, Melbourne

Hypertension & Kidney Disease / Huma Neurotransmitter Laboratory, Melbourne

Centre Hospitalier Universitaire du Sart-Tilman, Liège

Debreceni Egyetem - Klinikai Központ, Debrecen

Royal Perth Hospital Unit - The University of Western Australia, Perth

Curtin University, Faculty of Health Sciences, School of Public Health, Bentley

DRC Gyógyszervizsgáló Központ Kft., Balatonfüred

Universitair Ziekenhuis Gent Cardiologie, Ghent

Markusovszky Egyetemi Oktatókórház, Szombathely

O.F. Herbachevsky Zhytomyr Regional Clinical Hospital, Cardiology department, Zhytomyr

SCU Medicina Interna e Centro Ipertensione arteriosa. Dipartimento di Scienze Mediche Università di Torino, Aou Citta' Salute E Scienza Torino, Torino

Scott Research Inc, Laurelton

General Hospital of Athens, Ippokrateio, Athens

Albany Medical College, Albany

Jewish Hospital Berlin, Berlin

General Hospital Konstantopouleio-Patision, Nea Ionia

Great Lakes Medical Research LLC, Westfield

General Hospital of Athens Georgios Gennimatas, Athens

Interni oddeleni, Nefrologie, Prague

Asklepeion General Hospital, Athens

Hospital Virgen de las Nieves - Internal Medicine Department, Granada

Manassas Clinical Research Center, Manassas

Turku University Central Hospital - Turun yliopistollinen keskussairaala Sisätautien klinikka, Turku

MedStar Health Research Institute, Hyattsville

Ospedale San Gerardo, Clinica Medica, Monza

"Communal Non-profit Enterprise Vinnytsya regional Clinical Hospital named after. N.I. Pirogov Vinnytsia Regional Council/ National Pirogov Memorial Medical University, Vinnytsya", Vinnytsia

Burke Internal Medicine & Research, Burke

University Brescia Department Clinical and Experimental Science, Brescia

East Carolina University, Greenville

Physician's East Endocrinology, Greenville

Hospital Clinico San Carlos - Istituto de Investigacion Sanitaria San Carlos (IdISSC), Madrid

Hospital Universitario La Paz, Madrid

Metrolina Internal Medicine/Internal Medicine Research, Charlotte

Carteret Medical Group, Morehead City

TLM Medical Services LLC, Columbia

DeGarmo Institute of Medical Research, Greer

East Coast Institute for Research, Saint Augustine

Century Clinical Research, Inc, Daytona Beach

Premier Medical Associates, The Villages

Mayo Clinic Jacksonville, Jacksonville

Canvas Clinical Research, LLC, Lake Worth

Bay Area Cardiology Associates, P.A., Brandon

TAYS RDI center (Tampere University Hospital,Specialist Internal Medicine, Rare Diseases), Tampere

Advanced Cardiovascular, LLC, Alexander City

CHU Grenoble - Alpes, Grenoble

LifeDOC Research PLLC, Memphis

Stern Cardiovascular Foundation, Inc, Germantown

Universitätsklinikum Düsseldorf Klinik für Nephrologie, Düsseldorf

Hospital Virgen del Rocio Departamento de Medicina Interna, Seville

Volyn Regional Center for Cardiovascular Pathology, Rehabilitation Department, Lutsk

University Hospitals Cleveland Medical Center - Neurological Institute, Cleveland

Hospital Clínic Universitari de València, Valencia

Hypertension Clinic, Internal Medicine, Hospital Clinico, University of Valencia, Valencia, Valencia

Cardiovascular Research of Northwest Indiana, L.L.C., Munster

Midwest Institute for Clinical Research, Indianapolis

Reid Physician Associates, Richmond

Milwaukee Nephrologists, SC, Wauwatosa

Azienda Ospedaliero Universitaria Pisana - Department Clinical and Experimental Medicine, Pisa

"State Institution L.T. Malaya Therapy National Institute of the NAMS of Ukraine", Kharkiv

"Municipal non-profit enterprise Clinical Hospital # 8of Kharkiv City Council", Kharkiv

SIU School of Medicine Center for Clinical Research, Springfield

Clinical Research Consultants, LLC, Kansas City

Universitätsklinikum des Saarlandes, Homburg/Saar

Hôpital de la Croix-Rousse - Rhône, Lyon

Grace Research, LLC, Bossier City

Hôpital Européen Georges Pompidou- Centre d' Investigation Clinique, Paris

LinQ Research, LLC, Pearland

Mercury Clinical Research, Webster

Danylo Halytsky Lviv National Medical University, Lviv

Amarillo Heart Clinical Research Institute, Inc., Amarillo

Centre Hospitalier Intercommunal Toulon La Seyne sur Mer, Toulon

St. George Kidney Care LLC dba Southern Utah Kidney and Hypertension Center, St. George

Renal Medicine Associates, Albuquerque

Academic Medical Research Institute Inc, Los Angeles

University of Oulu, Medical Research Center, Oulu

Chrishard Medical Group, Inglewood

Universitätsklinikum Nürnberg Süd, Nuremberg

Universitätsklinikum Erlangen Klinische Forschungsstation (CRC), Erlangen

Amicis Research Center, Northridge

California Kidney Specialists, San Dimas

Clinical Trials Research, Lincoln

Willamette Valley Clinical Studies, Eugene

National Medical Research Center for Preventive Medicine, Moscow

"State Budgetary Healthcare Institution of Arkhangelsk Region First City Clinical Hospital n.a. E.E. Volosevich", Arkhangelsk

Federal State Military Educational Institution of Higher Professional Education, Military Medical Academy named for S. M. Kirov of the Ministry of Defense of the Russian Federation, Saint Petersburg

"Federal State Budget Institution National Medical Research Center n.a. V.A. Almazov of the Ministry of healthcare of the Russian Federation", Saint Petersburg

Federal State Budget Institution National Medical Research Center n.a. V.A. Almazov of the Ministry of Healthcare of the Russia, Saint Petersburg

Ruijin Hospital Shanghai Jiaotong University School of Medicine, Shanghai

State Budgetary Educational Institution of Higher Professional Education Smolensk State Medical Academy, Smolensk

Zhejiang Province People's Hospital, Hangzhou

Scientific Research Institute - Regional Clinical Hospital №1, Krasnodar

The Third Xiangya Hospital of Central South University, Changsha

"State Healthcare Institution Regional Clinical Cardiology Dispensary", Saratov

"Federal State Budget Educational Institution of Higher Education Saratov State Medical University n.a. V.I. Razumovskiy of the Ministry of Healthcare of the Russian Federation", Saratov

"Federal State Autonomous Institution of Higher Education Kazan (Volga Region) Federal University", Kazan'

Guangdong General Hospital, Guangzhou

Hainan NO.3 Provincial people's Hospital, Sanya

Tyumen Cardiology Research Center, Tomsk National Research Medical Center, Russian Academy of Science, Tyumen

"State budget healthcare institution of Novosibirsk region City clinical hospital #34", Novosibirsk

"Federal State Budget Scientific Institution Federal Research Center Institute of Cytology and Genetics of Siberian Department of Russian Academy of Sciences", Novosibirsk

"Federal State Budget Scientific Institution Tomsk National Research Medical Center of the Russian Academy of Sciences", Tomsk

"Federal State Budget Scientific Institution Scientific Research Institute for Complex Issues of Cardiovascular Diseases", Kemerovo

The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an

Haemek Medical Center, Afula

Galilee Medical Center, Nahariya

Sheba Medical Center, Tel Litwinsky

Barzilai Medical Center, Cardiovascular Institute, Ashkelon

Shaare Zedek Medical Center, Jerusalem

Hypertension and Nephrology Association PA, Eatontown

Manna Research Inc (North Burlington), Hamilton

London Health Sciences Centre - Victoria Hospital, London

Canadian Phase Onward Inc., Toronto

Stephen S. Chow Medicine Professional Corporation, Toronto

Clinical Research Solutions Inc., Waterloo

The First Affiliated Hospital of Baotou Medical College of Inner Mongolia, Baotou

FN U Sv.Anny Brno, kardiologická klinika, Brno

Všeobecní fakultní nemocnice Praha, Prague

Thomayerova nemocnice, Prague

Kardio Václavík s.r.o, Přerov

Herzzentrum Leipzig Universitätsklinik für Kardiologie, Leipzig

Azienda Ospedaliera S. Andrea di Roma - Division of Cardiology and of Cardiothoracic and Vascular Science Department -, Roma

"JSC InMedica", Kaunas

Clinic of Cardiology and Rehabilitation, Klaipėda

Academic Medical Center Amsterdam, Amsterdam

Zuyderland Medical Center, Geleen

Maastricht University Medical Center, Dept. of Medicine, Maastricht

Radboud University Medical Center, Nijmegen

Uniwersyteckie Centrum Kliniczne Centrum Kardiologii, Gdansk

Samodzielny Publiczny Szpital Kliniczny im. Andrzeja Mielęckiego Śląskiego Uniwersytetu Medycznego w Katowicach, Katowice

Diamond Clinic, Krakow

SPZOZ Centralny Szpital Kliniczny Uniwersytetu Medycznego w Łodzi, Lodz

KO-MED. CentraKliniczne Sp. Z o.o. Ośrodek Badań Klinicznych w Lublinie II, Lublin

ETG Lublin, Lublin

Etyka Ośrodek Badań Klinicznych, Olsztyn

KO-MED. Centra Kliniczne Sp. Z o.o. Ośrodek Badań Klinicznych w Puławach, Puławy

ETG Skierniewice, Skierniewice

Medycyna Kliniczna, Warsaw

Samodzielny Publiczny Centralny Szpital Kliniczny w Warszawie, Warsaw

ETG Warszawa, Warsaw

Klinika Wad Wrodzonych Serca Instytut Kardiologii im. Kardynala Wyszynskiego, Warsaw

Samodzielny Publiczny Szpital Wojewódzki im. Papieża Jana Pawła II w Zamościu, Zamość

ETG Zgierz, Zgierz

Hospital del Mar, Barcelona

Fundació Puigvert, Barcelona

Hospital Vall d'Hebron de Barcelona, Barcelona

Hospital Universitari de Bellvitge, Barcelona

Kyiv City Clinical Hospital # 1, Kyiv

Kyiv Municipal Clinical Emergency Hospital, Kyiv

"State Institution National Scientific Center M.D. Strazhesko Institute of Cardiology of the National Academy of Medical Sciences of Ukraine", Kyiv

"State Institution D.F. Chebotarev Institute of Gerontology, National Academy of Medical Science of Ukraine", Kyiv

"State Institution Institute of Gerontology named after D.F. Chebotarev of National Academy of Medical Sciences of Ukraine", Kyiv

Aberdeen Royal Infirmary, Clinical Pharmacology Unit, Aberdeen

Clinical Research Centre The University of Edinburgh Centre for Cardiovascular Science, Edinburgh

Queen Mary University of London, London