Early Discontinuation of Empirical Antifungal Therapy and Biomarkers

NARecruitingINTERVENTIONAL
Enrollment

194

Participants

Timeline

Start Date

June 6, 2018

Primary Completion Date

June 30, 2024

Study Completion Date

June 30, 2025

Conditions
Invasive Candidiasis
Interventions
OTHER

Biomarker strategy

EAT duration is determined by β-D-1,3-glucan and mannan serum assays, performed at day 0 (day of EAT initiation) and day 3.

OTHER

Routine strategy

EAT duration is based on IDSA guidelines, which recommend 14 days of treatment for patients without subsequent proven ICI, and who improve under antifungal treatment, or less in other situations.

Trial Locations (10)

Unknown

RECRUITING

CH ARRAS, Arras

RECRUITING

CH de DOUAI, Douai

RECRUITING

CH Dunkerque, Dunkirk

RECRUITING

Centre Hospitalier Dr Schaffner, Lens

RECRUITING

Ch Dr.Schaffner de Lens, Lens

RECRUITING

Hôpital Roger Salengro, CHU, Lille

RECRUITING

CH Roubaix, Roubaix

RECRUITING

CHU de Rouen, Rouen

RECRUITING

Ch Tourcoing, Tourcoing

RECRUITING

Centre hospitalier de valenciennes, Valenciennes

All Listed Sponsors
lead

University Hospital, Lille

OTHER