A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to an Active Comparator in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis

PHASE3CompletedINTERVENTIONAL
Enrollment

743

Participants

Timeline

Start Date

June 13, 2018

Primary Completion Date

September 12, 2019

Study Completion Date

August 9, 2023

Conditions
Chronic Plaque PsoriasisModerate to Severe Chronic Plaque Psoriasis
Interventions
DRUG

Bimekizumab

Subjects will receive bimekizumab at pre-specified time-points.

DRUG

Secukinumab

Subjects will receive secukinumab at pre-specified time-points.

OTHER

Placebo

Subjects will receive placebo at pre-specified time-points to maintain the blinding in the double-blind Treatment Period.

Trial Locations (77)

11415

Ps0015 965, Kew Gardens

27262

Ps0015 969, High Point

28405

Ps0015 971, Wilmington

30328

Ps0015 966, Sandy Springs

32174

Ps0015 921, Ormond Beach

33028

Ps0015 977, Pembroke Pines

33409

Ps0015 970, West Palm Beach

33613

Ps0015 936, Tampa

33614

Ps0015 976, Tampa

34470

Ps0015 903, Ocala

43209

Ps0015 980, Bexley

50265

Ps0015 900, West Des Moines

60077

Ps0015 954, Skokie

60118

Ps0015 972, West Dundee

63105

Ps0015 915, Clayton

63141

Ps0015 953, St Louis

70115

Ps0015 944, New Orleans

75246

Ps0015 979, Dallas

77004

Ps0015 924, Houston

78660

Ps0015 978, Pflugerville

92701

Ps0015 975, Santa Ana

97210

Ps0015 920, Portland

97223

Ps0015 929, Portland

06810

Ps0015 939, Danbury

03801

Ps0015 901, Portsmouth

Unknown

PS0015 3, Carlton

PS0015 7, Hectorville

PS0015 6, Kogarah

Ps0015 11, Parkville

PS0015 9, Woolloongabba

Ps0015 50, Brussels

Ps0015 54, Brussels

Ps0015 52, Liège

Ps0015 673, Halifax

Ps0015 671, Hamilton

Ps0015 663, Mississauga

Ps0015 661, Peterborough

Ps0015 678, Richmond Hill

Ps0015 677, Toronto

Ps0015 657, Waterloo

Ps0015 153, Toulouse

Ps0015 223, Augsburg

Ps0015 237, Berlin

Ps0015 211, Hamburg

Ps0015 215, Lübeck

Ps0015 213, Mahlow

Ps0015 238, Mainz

Ps0015 234, München

Ps0015 219, Münster

Ps0015 236, Neu-Ulm

Ps0015 222, Tübingen

Ps0015 204, Witten

Ps0015 265, Amsterdam

Ps0015 263, Breda

Ps0015 355, Bialystok

Ps0015 361, Bialystok

Ps0015 369, Bialystok

Ps0015 352, Gdansk

Ps0015 366, Katowice

Ps0015 378, Katowice

Ps0015 376, Krakow

Ps0015 379, Krakow

Ps0015 372, Lodz

Ps0015 377, Ostrowiec Świętokrzyski

Ps0015 368, Wroclaw

Ps0015 375, Wroclaw

Ps0015 455, Alicante

Ps0015 450, Barcelona

Ps0015 451, Madrid

Ps0015 454, Madrid

Ps0015 456, Madrid

Ps0015 457, Sant Joan Despí

Ps0015 763, Gaziantep

Ps0015 762, Istanbul

Ps0015 760, Kayseri

Ps0015 559, Newcastle upon Tyne

Ps0015 555, Salford

All Listed Sponsors
lead

UCB Biopharma SRL

INDUSTRY

NCT03536884 - A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to an Active Comparator in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis | Biotech Hunter | Biotech Hunter