To Explore Cognitive Neural Mechanism of Autoimmune Encephalitis by Using Neuropsychological Tests and Multi-modal MRI

CompletedOBSERVATIONAL
Enrollment

22

Participants

Timeline

Start Date

April 7, 2017

Primary Completion Date

February 28, 2018

Study Completion Date

February 28, 2018

Conditions
Cognitive ImpairmentAutoimmune Encephalitis
Interventions
DRUG

rituximab

375 mg/m2 weekly for 4 weeks

DRUG

cyclophosphamide

750 mg/m2 monthly for 4-6 cycles depending on the response

DRUG

Steroids

500-1000 mg of methylprednisolone daily for 3 days, then tapered doses

DRUG

Intravenous immunoglobulin

intravenous immunoglobulin (IVIG) with or without plasmapheresis

Trial Locations (1)

Unknown

The First Affiliated Hospital, Zhejiang University, Hangzhou

All Listed Sponsors
lead

First Affiliated Hospital of Zhejiang University

OTHER

NCT03530462 - To Explore Cognitive Neural Mechanism of Autoimmune Encephalitis by Using Neuropsychological Tests and Multi-modal MRI | Biotech Hunter | Biotech Hunter