Project Remission: Maximizing Outcomes With Intensive Treatments for Combat-Related PTSD

NACompletedINTERVENTIONAL
Enrollment

234

Participants

Timeline

Start Date

January 27, 2017

Primary Completion Date

November 22, 2019

Study Completion Date

May 1, 2021

Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
BEHAVIORAL

Massed Prolonged Exposure

Participants will complete fifteen weekday 90-minute Prolonged Exposure therapy sessions over three consecutive weeks. If necessary, the treatment window may be extended for another week.

BEHAVIORAL

Intensive Outpatient Prolonged Exposure

The IOP-PE will include the same primary treatment components as the Massed-PE protocol (fifteen weekday 90-minute PE sessions delivered five days a week over a three-week period) plus eight augmentations designed to maximize treatment outcomes. Similar to the Mass-PE, participants will have three consecutive weeks to complete treatment; however, the treatment window may be extended another week if necessary.

Trial Locations (4)

76504

Central Texas Veterans Health Care System, Waco

76544

Carl R. Darnall Army Medical Center, Fort Hood

78229

South Texas Veterans Health Care System, San Antonio

78234

Brooke Army Medical Center, San Antonio

All Listed Sponsors
collaborator

Brooke Army Medical Center

FED

collaborator

South Texas Veterans Health Care System

FED

collaborator

C.R.Darnall Army Medical Center

FED

collaborator

Central Texas Veterans Health Care System

OTHER

collaborator

VISN 17 Center of Excellence

FED

collaborator

University of Pennsylvania

OTHER

lead

The University of Texas Health Science Center at San Antonio

OTHER

NCT03529435 - Project Remission: Maximizing Outcomes With Intensive Treatments for Combat-Related PTSD | Biotech Hunter | Biotech Hunter