Study of Porcine Fibrin Sealant in Preventing Cervical Anastomotic Leakage for Esophageal or Junctional Carcinoma.

PHASE2CompletedINTERVENTIONAL
Enrollment

57

Participants

Timeline

Start Date

June 1, 2018

Primary Completion Date

March 31, 2019

Study Completion Date

August 22, 2021

Conditions
Esophageal CancerGastroesophageal Junction CancerAnastomotic Leak
Interventions
BIOLOGICAL

Porcine Fibrin Sealant (PFS)

2.5ml Porcine Fibrin Sealant will be instilled over the cervical anastomose line.

PROCEDURE

Surgery

McKeown esophagectomy including open or minimally invasive esophagectomy will be performed for patients with resectable thoracic esophageal carcinoma or gastroesophageal junction cancer. Two-field lymphadenectomy with total mediastinal lymph node dissection is performed during surgery. At last, 2.5ml Porcine Fibrin Sealant will be instilled over the cervical anastomose line.

Trial Locations (1)

510060

Sun Yat-sen University Cancer Center, Guangzhou

All Listed Sponsors
lead

Sun Yat-sen University

OTHER

NCT03529266 - Study of Porcine Fibrin Sealant in Preventing Cervical Anastomotic Leakage for Esophageal or Junctional Carcinoma. | Biotech Hunter | Biotech Hunter