Occipital Blocks for Acute Migraine

PHASE3CompletedINTERVENTIONAL
Enrollment

63

Participants

Timeline

Start Date

April 3, 2019

Primary Completion Date

March 10, 2023

Study Completion Date

March 10, 2023

Conditions
Chronic Migraine, HeadacheEpisodic Migraine
Interventions
DRUG

Lidocaine 4% Topical Application Cream [LMX 4]

Run-in Step: All subjects receive 32 mg (4 cm ribbon of cream) applied, bilaterally, over greater occipital nerve.

DRUG

Lidocaine Hydrochloride 2 mg/mL Injectable Solution

Subjects, who continue to experience headache pain after the run-in step, receive 2 (2 mL) injections of the active treatment.

DRUG

Normal Saline

Subjects, who continue to experience headache pain after the run-in step, receive 2 (2 mL) injections of the comparator.

Trial Locations (1)

19104

Children's Hospital of Philadelphia, Philadelphia

All Listed Sponsors
collaborator

National Institute of Neurological Disorders and Stroke (NINDS)

NIH

lead

Children's Hospital of Philadelphia

OTHER

NCT03526874 - Occipital Blocks for Acute Migraine | Biotech Hunter | Biotech Hunter