113
Participants
Start Date
August 3, 2018
Primary Completion Date
December 28, 2018
Study Completion Date
December 28, 2018
VX-445/TEZ/IVA
Participants received VX-445/TEZ/IVA orally once daily in the morning.
TEZ/IVA
Participants received TEZ/IVA orally once daily in the morning.
IVA
Participants received IVA orally once daily in the evening.
Placebo
Participants received placebo matched to VX-445/TEZ/IVA orally once daily in the morning.
Placebo
Participants received placebo matched TEZ/IVA orally once daily in the morning.
New York Medical College, Valhalla
Children's Hospital of Philadelphia, Philadelphia
University of Virginia Primary Care Center, Charlottesville
West Virginia University, Morgantown
UNC Marisco Clinical Research Center, Chapel Hill
Medical University of South Carolina, Charleston
Central Florida Pulmonary Group, PA, Orlando
Nemours Children's Hospital, Orlando
Joe DiMaggio Cystic Fibrosis & Pulmonary Center/ Joe DiMaggio Children's Hospital/ Memorial Regional Hospital, Hollywood
Tampa General Hospital Cardiac and Lung Transplant Clinic, Tampa
Nationwide Children's Hospital, Columbus
ProMedica Toledo Hospital/ Toledo Children's Hospital/ Pediatric Pulmonary & Cystic Fibrosis Center, Toledo
Rainbow Babies and Children's Hospital/University Hospitals Cleveland Medical Center, Cleveland
Dayton Children's Hospital, Dayton
Harper University Hospital, Detroit
Northwestern Memorial Hospital, Chicago
Saint Francis Medical Center/ Children's Hospital of Illinoise/OSF, Peoria
Tulane Medical Center, New Orleans
University of Arkansas for Medical Sciences, Little Rock
University of Oklahoma Health Sciences Center, Oklahoma City
The University of Texas Southwestern Medical Center, Dallas
National Jewish Health, Denver
Banner University of Arizona Medical Center, Tucson
Children's Hospital Los Angeles, Los Angeles
Miller Children's Hospital/ Long Beach Memorial, Long Beach
Valley Children's Hospital, Madera
Massachusetts General Hospital Cystic Fibrosis Center Clinical Research Center, Boston
Vermont Lung Center, Colchester
Cliniques Universitaires de Bruxelles Hopital Erasme, Brussels
Universitair Ziekenhuis Brussel - Campus Jette, Brussels
UZ Antwerpen, Edegem
Universitair Ziekenhuis Gent, Ghent
Universitaire Ziekenhuizen Leuven - Campus Gasthuisberg, Leuven
Academic Medical Center, Amsterdam
University Medical Center, Utrecht, Department of Pulmonology and Tuberculosis, Heidelberglaan
UMC St. Radboud, Nijmegen
Erasmus Medical Center, Rotterdam
HagaZiekenhuis van den Haag, The Hague
The Royal Belfast Hospital for Sick Children, Belfast
Heart of England NHS Foundation Trust, Birmingham Heartlands Hospital, Birmingham
Royal Devon and Exeter NHS Foundation Trust, Royal Devon and Exeter Hospital, Exeter
Leeds General Infirmary, Leeds
King's College Hospital, London
Southampton General Hospital, Southampton
Vertex Pharmaceuticals Incorporated
INDUSTRY