Lung Pharmacokinetics (PK) in Epithelial Lining Fluid (ELF)

NACompletedINTERVENTIONAL
Enrollment

21

Participants

Timeline

Start Date

April 10, 2018

Primary Completion Date

December 31, 2018

Study Completion Date

December 31, 2018

Conditions
Healthy
Interventions
DRUG

Inhalation

Salbutamol(200µg), Salmeterol (50µg) and Fluticasone propionate (500µg) by inhalation

DRUG

Systemic

Salbutamol 8mg M/R Tablet, Propranolol 40 mg administered orally

OTHER

Bronchoscopy

Bronchoadsorption sample, bronchial brushing, mucosal biopsy, and BAL samples during bronchoscopy

Trial Locations (1)

30625

Fraunhofer Institute for Toxicology and Experimental Medicine, Hanover

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

lead

Fraunhofer-Institute of Toxicology and Experimental Medicine

OTHER