Drug-drug Interactions Between Antiretroviral Drugs and Cardiovascular Drugs in Elderly Patients

CompletedOBSERVATIONAL
Enrollment

21

Participants

Timeline

Start Date

April 23, 2018

Primary Completion Date

August 29, 2019

Study Completion Date

August 29, 2019

Conditions
HIV InfectionsDrug InteractionsCardiovascular Diseases
Interventions
DRUG

Co-administration of darunavir with a cardiovascular drug

Co-administration of darunavir, an HIV agent considered prone to induce drug interactions, with a cardiovascular drug (amlodipine, atorvastatin or rosuvastatin). Note that a patient will be able to participate in the intervention group and the control group if a change in his/her anti-HIV treatment occurs (study partly parallel and partly in cross-over).

Trial Locations (2)

1011

Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne

4031

Universitätsspital Basel, Basel

All Listed Sponsors
lead

Centre Hospitalier Universitaire Vaudois

OTHER

NCT03515772 - Drug-drug Interactions Between Antiretroviral Drugs and Cardiovascular Drugs in Elderly Patients | Biotech Hunter | Biotech Hunter