Dexmedetomidine and Propofol for Pediatric MRI Sedation

propofol 2 mg/kg at start of procedure; 2 mg/kg for movement, 150-300 mcg/kg/minute propofol infusion if movement persists

single dose dexmedetomidine administered at start of sedation in the propofol-dexmedetomidine group. Dosing is based upon anticipated duration of scan from 30 - 75 minutes and will range from 0.5 mic/kg to 1.25 mcg/kg

4 mcg/kg glycopyrrolate will be administered at the start of sedation in the propofol-dexmedetomidine group

1 mg/kg intravenous administration prior to propofol administration

Inhalation of nitrous oxide may be used for IV placement

Inhalation of sevoflurane may be used for IV placement