400
Participants
Start Date
October 22, 2018
Primary Completion Date
July 30, 2020
Study Completion Date
February 28, 2021
Sofosbuvir/Velpatasvir (SOF/VEL)
400/100 mg fixed-dose combination (FDC) tablet administered orally once daily with or without food.
Minimal Monitoring (MINMON) Strategy
"MINMON Strategy:~1. No pre-treatment HCV genotyping~2. Entire treatment course (84) tablets of SOF/VEL administered to participants at study entry~3. No scheduled on-treatment laboratory monitoring or clinic visits~4. Remote contact with participants at week 4 and week 22"
University of the Witwatersrand Helen Joseph (WITS HJH) CRS (11101), Johannesburg
Family Clinical Research Unit (FAM-CUR) CRS (8950), Cape Town
Weill Cornell Chelsea CRS (7804), New York
Columbia Physicians and Surgeons CRS (30329), New York
Weill Cornell Upton CRS (7803), New York
Thai Red Cross AIDS Research Centre (TRC-ARC) CRS (31802), Bangkok
University of Rochester Adult HIV Therapeutic Strategies Network CRS (31787), Rochester
Pittsburgh CRS (1001), Pittsburgh
Hosp. of the Univ. of Pennsylvania CRS (6201), Philadelphia
Whitman Walker Health CRS (31791), Washington D.C.
Instituto de Pesquisa Clinica Evandro Chagas (12101), Rio de Janeiro
Johns Hopkins University CRS (201), Baltimore
Greensboro CRS (3203), Greensboro
Unc Aids Crs (3201), Chapel Hill
The Ponce de Leon Center CRS (5802), Atlanta
Alabama CRS (31788), Birmingham
Vanderbilt Therapeutics (VT) CRS (3652), Nashville
The Ohio State Univ. AIDS CRS (2301), Columbus
Case CRS (2501), Cleveland
Univ. of Cincinnati CRS (2401), Cincinnati
Chiang Mai University HIV Treatment CRS (31784), Chiang Mai
Northwestern University CRS (2701), Chicago
Rush Univ. Med. Ctr. ACTG CRS (2702), Chicago
Washington U CRS (2101), St Louis
Trinity Health and Wellness Center CRS (31443), Dallas
Houston AIDS Research Team CRS (31473), Houston
University of Colorado Hospital CRS (6101), Aurora
UCLA CARE Center CRS (601), Los Angeles
Ucsd, Avrc Crs (701), San Diego
Ucsf Aids Crs (801), San Francisco
Hospital Nossa Senhora da Conceicao CRS (12201), Porto Alegre
University of Southern California (1201), Los Angeles
Massachusetts General Hospital (MGH) CRS (101), Boston
Brigham and Women's Hosp. ACTG CRS (107), Boston
New Jersey Medical School Clinical Research Center CRS (31786), Newark
The Miriam Hospital ACTG CRS (2951), Providence
Puerto Rico-AIDS CRS (5401), San Juan
Joint Clinical Research Centre (JCRC) (12401), Kampala
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
NETWORK