Remote Limb Ischemic Conditioning to Enhance Learning and Muscle Strength in Healthy Young Adults

PHASE1CompletedINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

November 8, 2017

Primary Completion Date

December 31, 2018

Study Completion Date

January 31, 2019

Conditions
Healthy, Young Adults
Interventions
BEHAVIORAL

RLIC

See descriptions under arm/group descriptions. RLIC is delivered for 8 visits. Visits 1-3 occur on consecutive work days and visits 4-8 occur on alternating week days.

BEHAVIORAL

Sham conditioning

See descriptions under arm/group descriptions. Sham conditioning is delivered for 8 visits. Visits 1-3 occur on consecutive work days and visits 4-8 occur on alternating week days.

BEHAVIORAL

Muscle strength training

All participants undergo muscle strength training of the wrist extensor muscles on one side. Strength training follows standard American College of Sports Medicine guidelines for frequency, intensity, progression etc. Strength training is provided at visits 3-8

BEHAVIORAL

Driving training

All participants undergo training of a complex cognitive-motor task using a driving simulator. Participants learn to 'drive' on a virtual course, maximizing speed and minimizing errors. Participants perform the driving task once each day for visits 3-8.

BEHAVIORAL

Balance training

All participants undergo training on a balance board, learning to hold the board level with equal weight on each leg. Participants perform the balance task for 15, 30-second trials per day at visits 3-8.

Trial Locations (1)

63108

Washington University School of Medicine, St Louis

All Listed Sponsors
collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

lead

Washington University School of Medicine

OTHER

NCT03512028 - Remote Limb Ischemic Conditioning to Enhance Learning and Muscle Strength in Healthy Young Adults | Biotech Hunter | Biotech Hunter