10
Participants
Start Date
January 31, 2018
Primary Completion Date
November 22, 2022
Study Completion Date
June 1, 2023
Intratympanic injection
Injection will be up to 1cc of dexamethasone 24mg/mL. The procedure will be performed at supine position under a microscope. Local anesthesia will be achieved with topical phenol. A myringotomy will be made in the tympanic membrane. A 1 mL syringe connected to a needle will be used to slowly inject between 0.2 cc and 1.0 cc of solution through the myringotomy, with the subject's head turned 45 degrees to the opposite side. The subject will be asked to maintain positioning for at least 30 minutes and refrain from swallowing. The dose administered will vary due to subject-specific factors.
Prednisone
Oral Steroid
University of Missouri, Columbia
University of Missouri-Columbia
OTHER