71
Participants
Start Date
April 10, 2018
Primary Completion Date
January 31, 2020
Study Completion Date
October 8, 2022
Brentuximab Vedotin - induction
Brentuximab vedotin 1.8 mg/kg at D8 of a 28-day cycle - 4 cycles = 16 weeks for combined chemotherapy
Gemcitabine
Gemcitabine 1000 mg/m² at D1 and D15 of a 28-day cycle - 4 cycles = 16 weeks for combined chemotherapy
Brentuximab Vedotin - maintenance
"Patients who will obtain partial or complete response and who will not be eligible for transplant will receive maintenance therapy with brentuximab vedotin every 3 weeks for 12 infusions.~Brentuximab vedotin 1.8 mg/kg at D1 of a 21-day cycle - 12 cycles = 36 weeks for maintenance therapy"
autologous or allogeneic stem cell transplantation
Patients who will obtain partial or complete response and who will be eligible for transplant will receive autologous or allogeneic stem cell transplantation
Clinique Universitaire Saint LUC, Brussels
ZNA Stuivenberg, Antwerp
CHU de Liege, Liège
A. Z. Sint-Jan, Bruges
UZ Gent, Ghent
CHU de Dijon - Hôpital le Bocage, Dijon
CHU de Besançon - Hôpital Jean Minjoz, Besançon
CHU de Toulouse, Toulouse
Centre François Magendie - Hôpital du Haut Lévêque, Pessac
CH Saint-Eloi, Montpellier
CHU De Rennes, Rennes
CHRU de Tours, Tours
CHU Grenoble, Grenoble
CHU de Nantes - Hôtel Dieu, Nantes
CHU Angers, Angers
CHU Nancy - Brabois, Nancy
CH de Valenciennes, Valenciennes
CHU d'Estaing, Clermont-Ferrand
CH Côte Basque, Bayonne
CH de Mulhouse Sud Alsace, Mulhouse
Centre Leon Berard, Lyon
Centre Hospitalier Lyon Sud, Pierre-Bénite
CH du Mans, Le Mans
CH Chambéry, Chambéry
Centre Hospitalier Annecy Genevois, Metz-Tessy
APHP - Hôpital Necker, Paris
APHP - Hôpital Saint Louis, Paris
Centre Henri BECQUEREL, Rouen
CH de Versailles - Hopital André Mignot, Le Chesnay
IHBN - CHU Cote de Nacre, Amiens
CH d'Avignon - Hôpital Henri Dufaut, Avignon
CHU de Poitiers - Hôpital de la Milétrie, Poitiers
APHP - Hopital Henri Mondor, Créteil
Institut Jules Bordet, Brussels
ULB Hôpital Erasme, Brussels
CHU UCL Namur, Yvoir
CHU d'Amiens, Amiens
CHRU de Lille - Hôpital Claude Huriez, Lille
CHU de Limoges, Limoges
The Lymphoma Academic Research Organisation
OTHER