Treatment of Hypoglycemia in Type 1 Diabetes

NACompletedINTERVENTIONAL
Enrollment

29

Participants

Timeline

Start Date

April 18, 2018

Primary Completion Date

August 31, 2020

Study Completion Date

August 31, 2020

Conditions
Type 1 Diabetes
Interventions
OTHER

Induced-hypoglycemia test

Participants will be admitted at the research center at 7:00 after an overnight fast. A venous catheter will be inserted into an arm vein for blood sampling purposes. A subcutaneous insulin bolus will be administered to induce hypoglycemia. Oral treatment (16g of carbohydrates or 32g of carbohydrates) will be given when plasma glucose levels are at the target threshold of \< 3.0 mmol/L or 3.0-3.5 mmol/L. Hypoglycemia symptoms will be assessed every 10 minutes by the participant using a validated scale starting from the time of insulin bolus until hypoglycemia recovery. One hour after hypoglycemia recovery, a standardized meal will be given.

Trial Locations (1)

Unknown

Institut de recherches cliniques de Montréal, Montreal

All Listed Sponsors
lead

Institut de Recherches Cliniques de Montreal

OTHER

NCT03489967 - Treatment of Hypoglycemia in Type 1 Diabetes | Biotech Hunter | Biotech Hunter