A Study to Examine the Effect of Tesofensine and Metoprolol on the 24-hour Mean Heart Rate

PHASE1CompletedINTERVENTIONAL
Enrollment

37

Participants

Timeline

Start Date

July 11, 2018

Primary Completion Date

June 6, 2019

Study Completion Date

June 6, 2019

Conditions
Phase 1
Interventions
DRUG

Metoprolol Succinate 25 MG

A single dose of 25 mg metoprolol ER in the morning of Day 15, Day 18 or Day 21 approximately 30 minutes after start of a standard breakfast and together with the tesofensine dose.

DRUG

Metoprolol Succinate 50 MG

A single dose of 50 mg metoprolol ER in the morning of Day 15, Day 18 or Day 21 approximately 30 minutes after start of a standard breakfast and together with the tesofensine dose.

DRUG

Metoprolol Succinate 100 MG

A single dose of 100 mg metoprolol ER in the morning of Day 15, Day 18 or Day 21, approximately 30 minutes after start of a standard breakfast and together with the tesofensine dose.

Trial Locations (1)

14050

Parexel International GmbH; Early Phase Clinical Unit Berlin, Berlin

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Saniona

INDUSTRY