White Matter Hyperintensities Burden in Adult Patients With Cyanotic Congenital Heart Disease: a Pilot Study

CompletedOBSERVATIONAL
Enrollment

146

Participants

Timeline

Start Date

October 17, 2017

Primary Completion Date

December 31, 2021

Study Completion Date

December 31, 2021

Conditions
Aging, PrematureCongenital Heart DiseaseWhite Matter Hyperintensities
Interventions
OTHER

Brain MRI

Acquisition of 3D T1-weighted, 3D FLAIR and GRE brain MRI scans

OTHER

Neuropsychological test battery

"1. Mini Mental State Examination (MMSE), Measso et al. (1993);~2. Frontal Assessment Battery (FAB), Appollonio et al. (2005);~3. Symbol Digit Test, Amodio et al. (2002);~4. Digit Cancellation Test, Della Sala et al. (1992);~5. Trial Making Test (TMT A-B), Giovagnoli et al. (1996);~6. Weigl's Sorting Test, Laicona et al. (2000) and Inzaghi (2010);~7. Digit Span, Orsini et al (1987);~8. Corsi block-tapping test, Orsini et al. (1987);~9. Babcock story recall test, Carlesimo et al. (2002);~10. Phonemic verbal fluency in MDB, Caltagirone and Carlesimo (2010);~11. Semantic verbal fluency, Novelli (1986);~12. Imitating gestures, De Renzi et al. (1980);~13. Coloured Progressive Matrices (CPM47), Measso et al. (1993)."

Trial Locations (1)

20097

IRCCS Policlinico San Donato, San Donato Milanese

All Listed Sponsors
lead

IRCCS Policlinico S. Donato

OTHER

NCT03487302 - White Matter Hyperintensities Burden in Adult Patients With Cyanotic Congenital Heart Disease: a Pilot Study | Biotech Hunter | Biotech Hunter