Coronary Microvascular Function and CT Coronary Angiography (CorCTCA)

NAActive, not recruitingINTERVENTIONAL
Enrollment

250

Participants

Timeline

Start Date

August 31, 2017

Primary Completion Date

December 20, 2023

Study Completion Date

August 31, 2033

Conditions
Angina, StableAngina Pectoris, VariantMicrovascular Angina
Interventions
DIAGNOSTIC_TEST

Stratified medicine involving a diagnostic intervention

"Adjunctive tests of coronary artery lesion severity (fractional flow reserve) and function at the time of invasive coronary angiography. Diagnostic groups: stable coronary syndromes in patients with obstructive coronary artery disease (mis-classified by non-invasive CTCA) or no-obstructive coronary disease including the following sub-groups (coronary artery vasospasm, microvascular spasm, impaired vasorelaxation due to (1) endothelial dysfunction and/or (2) non-endothelial dysfunction, or unaffected (normal test results).~Medical management is linked to contemporary clinical guidelines for the management of patients with stable coronary artery disease (European Society of Cardiology (2013), Scottish Intercollegiate Guideline Network (SIGN), 2017)."

DIAGNOSTIC_TEST

Stratified medicine involving a diagnostic intervention

"Adjunctive tests of coronary artery lesion severity (fractional flow reserve) and function at the time of invasive coronary angiography. Diagnostic groups: stable coronary syndromes in patients with obstructive coronary artery disease (mis-classified by non-invasive CTCA) or non-obstructive coronary disease including the following sub-groups (coronary artery vasospasm, microvascular spasm, impaired vasorelaxation due to (1) endothelial dysfunction and/or (2) non-endothelial dysfunction, or unaffected (normal test results).~Medical management is linked to contemporary clinical guidelines for the management of patients with stable coronary artery disease (European Society of Cardiology (2013), Scottish Intercollegiate Guideline Network (SIGN), 2017)."

Trial Locations (3)

G814DY

Golden Jubilee National Hospital, Clydebank

FK5 4WR

Forth Valley Royal Hospital, Larbert

G4 0SF

Glasgow Royal Infirmary, Glasgow

All Listed Sponsors
collaborator

University of Glasgow

OTHER

collaborator

British Heart Foundation

OTHER

collaborator

Chief Scientist Office of the Scottish Government

OTHER_GOV

collaborator

NHS Greater Clyde and Glasgow

OTHER

lead

NHS National Waiting Times Centre Board

OTHER

NCT03477890 - Coronary Microvascular Function and CT Coronary Angiography (CorCTCA) | Biotech Hunter | Biotech Hunter