NCT03476317View on ClinicalTrials.gov

Pilot Study of Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease

PHASE2CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

July 12, 2018

Primary Completion Date

December 31, 2020

Study Completion Date

December 31, 2020

Conditions

Crohn Disease

Interventions

DRUG

Vancomycin

Oral suspension 4 times daily (Day 1-14)

DRUG

Neomycin

Oral three times daily (Days 1-3)

DRUG

Ciprofloxacin

Oral twice daily (Days 4-14)

DRUG

Polyethylene Glycol 3350

Dissolved in Gatorade on day 2

DRUG

Fluconazole

Orally once daily (Day 1-14)

Trial Locations (1)

19146

Children's Hospital of Philadelphia, Philadelphia

All Listed Sponsors

collaborator

University of Pennsylvania

OTHER

collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

lead

Children's Hospital of Philadelphia

OTHER

NCT03476317 - Pilot Study of Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease | Biotech Hunter | Biotech Hunter