Comparing Several Strategies to Manage Moderate Acute Malnutrition Among Children From 6 to 24 Months Old

PHASE3CompletedINTERVENTIONAL
Enrollment

1,357

Participants

Timeline

Start Date

January 31, 2018

Primary Completion Date

December 31, 2018

Study Completion Date

June 30, 2019

Conditions
Moderate Acute Malnutrition
Interventions
DRUG

Azythromycin

Administration of azythromycin to the child at inclusion (3 days) 20 mgs/kgs/day : three days

DIETARY_SUPPLEMENT

Inuline and fructo-oligosaccharides

Administration of inuline and fructo-oligosaccharides (Synergy1) 2g/day, mixed with the fortified blend flour given to the child through the whole intervention.

DRUG

Albendazole

Administration of Albendazole at inclusion of the child : 200mgs, one administration

DIETARY_SUPPLEMENT

Fortified blend flour

"Children from 6 to 11 months : 200 grams / day Children from 12 to 24 months : 300 grams / day~Compostion of the fortified blend flour per 100 grams : either :~Mil (whole grains): 58,56 g/100g, Soybeans (fat meal): 16,54g/100g Peanuts (roasted seeds): 8,75g/100g, Cane sugar: 7,35 g/100g Whole milk (Powder): 7,56g/100g, MSV MAM: 0,28g/100g, iodized salt :0,45g/100g, CaC03: 0,48g/100g,Amylase BAN: 0,03g/100g OR Corn (whole grains): 53,29g/100g, Soybeans (dry seeds): 17,82g/100g, Peanuts (roasted seeds): 9,00 g/100g, Cane sugar: 11,00 Whole milk (Powder): 5,00g/100g, Soybean Oil (Purified): 1,24g/100g, Peanut oil (Purified): 1,13g/100g, MSV MAM: 0,27g/100g, iodized salt: 0,53 g/100g, Ca3(PO4)2: 0,62g/100g, KCl: 0,09g/100g"

Trial Locations (4)

101

Institut Pasteur de Madagascar - CRENAM Andohotapenaka et Centre de Santé Mitia, Antananarivo

BP 923

Institut Pasteur de bangui - Centre Nutritionnel de Gbangouma et Centre de Santé Saint-Joseph, Bangui

Unknown

Centre de santé intégré ACF de Tchake et d'Issawanne, Maradi

Institut Pasteur de Dakar - Poste de Santé Hamo V, Dakar

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Action Contre la Faim

OTHER

collaborator

Centre de Recherches Médicales et Sanitaires CERMES Niger

UNKNOWN

collaborator

Institut Pasteur de Madagascar

OTHER

collaborator

Institut Pasteur de Bangui

AMBIG

collaborator

Institut Pasteur de Dakar

OTHER

lead

Institut Pasteur

INDUSTRY

NCT03474276 - Comparing Several Strategies to Manage Moderate Acute Malnutrition Among Children From 6 to 24 Months Old | Biotech Hunter | Biotech Hunter