146
Participants
Start Date
February 21, 2018
Primary Completion Date
August 3, 2018
Study Completion Date
August 3, 2018
Placebo
HV: Lemborexant-matched oral placebo will be administered at bedtime in the clinic (within 5 minutes of lights off).
Lemborexant 10 mg
HV: 10 mg oral lemborexant will be administered at bedtime in the clinic (within 5 minutes of lights off).
Lemborexant 25 mg
HV: 25 mg oral lemborexant will be administered at bedtime in the clinic (within 5 minutes of lights off).
Placebo
OSA: Lemborexant-matched oral placebo will be administered at bedtime in the clinic (within 5 minutes of lights off) in the evening of Days 1 and 8. On Days 2 to 7, participants will take study drug at home, immediately (within 5 minutes) of the time they intend to try to sleep.
Lemborexant 10 mg
OSA: 10 mg oral lemborexant will be administered at bedtime in the clinic (within 5 minutes of lights off) in the evening of Days 1 and 8. On Days 2 to 7, participants will take study drug at home, immediately (within 5 minutes) of the time they intend to try to sleep.
Clinilabs Drug Development, New York
The Center for Sleep & Wake Disorders, Chevy Chase
Advarra, Columbia
Neurotrials Research, Inc, Atlanta
Research Centers of America, Hollywood
PAB Clinical Research, Brandon
CTI Clinical Research Center, Cincinnati
Community Research, Cincinnati
Pulmonary Associates, PA, Phoenix
PACT, Glendale
Pacific Research Network. LLC, San Diego
Purdue Pharma LP
INDUSTRY
Eisai Inc.
INDUSTRY