CYCLE: A Randomized Clinical Trial of Early In-bed Cycling for Mechanically Ventilated Patients

NAActive, not recruitingINTERVENTIONAL
Enrollment

360

Participants

Timeline

Start Date

October 15, 2018

Primary Completion Date

May 26, 2023

Study Completion Date

August 31, 2024

Conditions
Intensive Care Unit Acquired WeaknessCritical CareMechanical VentilationRespiratory Failure
Interventions
DEVICE

In-Bed Cycle Ergometer

Physiotherapists will place the patient's legs in a specialized in-bed cycle ergometer allowing for gentle leg exercise. Exercise can performed in passive, active-assisted, or active mode.

OTHER

Routine PT

Includes, based on the patient's alertness and medical stability, activities to maintain or increase limb range of motion and strength, in- and out- of bed mobility, ambulation, and assistance with optimizing airway clearance and respiratory function.

Trial Locations (16)

3084

Austin Health - Austin Hospital, Heidelberg

21201

University of Maryland Medical Centre, Baltimore

27710

Duke University Hospital, Durham

N3R 1G9

Brant Community Healthcare System - Brantford General Hospital, Brantford

L8L 2X2

Hamilton Health Sciences - Hamilton General Hospital, Hamilton

L8N 4A6

St. Joseph's Healthcare Hamilton, Hamilton

L8V 1C3

Hamilton Health Sciences - Juravinski Hospital, Hamilton

K7L 2V7

Kingston Health Sciences Centre - Kingston General Hospital, Kingston

N6A 5W9

London Health Sciences Centre - Victoria Hospital, London

K1H 8L6

The Ottawa Hospital - General Campus, Ottawa

K1Y 4E9

The Ottawa Hospital - Civic Campus, Ottawa

L2S 0A9

Niagara Health System - St. Catharines Site, St. Catharines

M5B 1W8

St. Michael's Hospital, Toronto

G6V 3Z1

Centre Integre de Sante et de Services Sociaux de Chaudiere-Appalaches - Hotel-Dieu de Levis, Lévis

H4J 1C5

Centre Integre Universitaire de Sante et de Services Sociaux du Nord-de-L'Ile-de-Montreal - Hopital du Sacre-Coeur de Montreal, Montreal

J1H 5N4

Centre Integre Universitaire de Sante et de services sociaux de l'Estrie - Centre hospitalier universitaire de Sherbrooke, Sherbrooke

All Listed Sponsors
collaborator

St. Joseph's Healthcare Hamilton

OTHER

collaborator

Canadian Institutes of Health Research (CIHR)

OTHER_GOV

collaborator

Canadian Critical Care Trials Group

OTHER

lead

McMaster University

OTHER

NCT03471247 - CYCLE: A Randomized Clinical Trial of Early In-bed Cycling for Mechanically Ventilated Patients | Biotech Hunter | Biotech Hunter