Double Immune Checkpoint Inhibitors in PD-L1-positive Stage IV Non-small Lung CancEr

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

265

Participants

Timeline

Start Date

May 2, 2018

Primary Completion Date

November 8, 2023

Study Completion Date

December 31, 2025

Conditions
Non-Small Cell Lung Cancer Metastatic
Interventions
DRUG

Ipilimumab

Ipilimumab 1 mg/kg every 6 weeks

DRUG

Nivolumab

Nivolumab 3 mg/kg every 2 weeks

Trial Locations (47)

14000

Caen - CHU Côte de Nacre, Caen

21000

Dijon - CAC, Dijon

40000

Mont de Marsan - CH, Mont-de-Marsan

44805

Nantes - Centre René Gauducheau, Nantes

45000

Orléans - CH, Orléans

46000

Cahors - CH, Cahors

49000

Angers - CHU, Angers

63000

Clermont Ferrand - CHU, Clermont-Ferrand

68000

Colmar - CH, Colmar

Mulhouse - CH, Mulhouse

72000

Centre Hospitalier - Pneumologie, Le Mans

74374

Annecy - CH, Annecy

75020

AP-HP Hopital Tenon - Pneumologie, Paris

76000

Rouen - CHU, Rouen

78157

Versailles - CH, Versailles

83000

Toulon - CHI, Toulon

85925

La Roche Sur Yon - CH, La Roche-sur-Yon

92140

Clamart - Hôpital Percy, Clamart

92151

Suresnes - Hopital Foch, Suresnes

95100

Argenteuil -CH, Argenteuil

Unknown

Amiens - CHU, Amiens

Avignon - CH, Avignon

Bordeaux - Polyclinique Nord, Bordeaux

Boulogne - Ambroise Paré, Boulogne-Billancourt

CH de Pontoise, Cergy-Pontoise

CH Chambery, Chambéry

CH de Chauny, Chauny

CH, Cholet

CHRU Grenoble, Grenoble

CHRU de Lille, Lille

CHU de Limoges, Limoges

CH Lyon Sud - Pneumologie, Lyon

Institut Paoli Calmette, Marseille

Marseille - Hôpital Européen, Marseille

Centre Antoine Lacassagne, Nice

CHU Nîmes, Nîmes

AP-HP Hôpital Bichat, Paris

GH Paris Saint-Joseph, Paris

Hôpital Saint Louis APHP, Paris

Paris - Institut Curie, Paris

Centre René Huguenin, Saint-Cloud

HIA Begin, Saint-Mandé

ICL Lucien Neuwirth, Saint-Priest-en-Jarez

CHU Toulouse, Toulouse

CHRU de Tours, Tours

CH de Villefranche - Pneumologie, Villefranche

02100

Saint Quentin - CH, Saint-Quentin

All Listed Sponsors
lead

Intergroupe Francophone de Cancerologie Thoracique

OTHER