The Study of Effectiveness of rTMS on Rumination and Anhedonia in Patients With Major Depressive Disorder

NACompletedINTERVENTIONAL
Enrollment

61

Participants

Timeline

Start Date

December 21, 2016

Primary Completion Date

September 30, 2020

Study Completion Date

October 30, 2020

Conditions
Major Depressive DisorderBipolar Depression
Interventions
DEVICE

Bilateral rTMS

The coil will locate on F3 and F4 in accordance with the 10-20 international system. bilateral rTMS include stimulate the right DLPFC at 1 Hz for a 10 seconds train of stimulation, and a total of 150 pulse trains. Immediately after that, the stimulation was carried out on the left DLPFC at 10 Hz, 5 seconds of stimulation, with 10 second inter-train interval and 75 pulse trains.

DEVICE

Sham rTMS

The same parameters will use in the sham rTMS. However, the coil adjust at an angle of 90º vertically on the skull in a way that one wing place on the head.

DEVICE

Unilateral rTMS (High frequency)

The coil will locate on F3 in accordance with the 10-20 international system. Unilateral rTMS include stimulate the Left DLPFC at 10Hz for a 5seconds train of stimulation, 10 seconds inter-train interval, and a total of 75 pulse trains. .

Trial Locations (1)

1969713663

Atieh Clinical Neuroscience Center (ACNC), Tehran

All Listed Sponsors
collaborator

Stanford University

OTHER

lead

University of Tehran

OTHER

NCT03468686 - The Study of Effectiveness of rTMS on Rumination and Anhedonia in Patients With Major Depressive Disorder | Biotech Hunter | Biotech Hunter