Effect of Ketorolac on Post Adenotonsillectomy Pain

PHASE4CompletedINTERVENTIONAL
Enrollment

63

Participants

Timeline

Start Date

July 19, 2018

Primary Completion Date

August 22, 2023

Study Completion Date

August 22, 2023

Conditions
Obstructive Sleep Apnea
Interventions
DRUG

Ketorolac

Patients in this group will receive 0.5mg/kg of ketorolac, administered intravenously.

DRUG

Standard of Care

"All patients will undergo inhalational induction with nitrous oxide and sevoflurane. After intravenous (IV) placement, 1-3mg/kg of propofol and 1mcg/kg of fentanyl will be administered. After induction, 0.5mg/kg of dexamethasone and an IV infusion of 15mg/kg of acetaminophen will be administered. During surgery, 0.5mcg/kg of dexmedetomidine and 0.1mg/kg ondansetron will be given.~A rescue dose of 0.5-1mcg/kg of IV Fentanyl will be available for use at the end of the procedure. The decision to administer will be left to the discretion of the attending anesthesiologist. The choice to give this will be made based on variables including patient's condition and a 20% increase in the heart rate and blood pressure.~The PACU nurses, who will be blinded to ketorolac administration, will evaluate the patients using FLACC scores. For patients with a FLACC score of 6-10, morphine 0.05mg/kg will be administered. For patients with FLACC scores of 3-5, morphine 0.025mg/kg will be administered."

Trial Locations (1)

30322

Childrens Healthcare of Atlanta, Egleston, Atlanta

All Listed Sponsors
lead

Emory University

OTHER

NCT03467750 - Effect of Ketorolac on Post Adenotonsillectomy Pain | Biotech Hunter | Biotech Hunter