Influence of Respiratory Gases Conditioning on Aerosol Delivery During Invasive Ventilation

NACompletedINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

January 22, 2018

Primary Completion Date

December 15, 2020

Study Completion Date

December 15, 2020

Conditions
Brain Injuries, Traumatic
Interventions
DEVICE

Aerogen Solo®

Aerosol particles are generated by a vibrating-mesh nebulizer specifically designed for mechanical ventilation

DEVICE

Heated-humidified circuit

It will be left on during the transfer and the nebulization in group 1

DEVICE

Heated-humidified circuit

It will be turned off 30 minutes before the nebulization (nebulization ended max 45 minutes after turning off the heated-humidifier).

DEVICE

Dry ventilator circuit specific for aerosol therapy

Streamlined components, specific position for the nebulizer at 30 cm of a V-shaped Y piece

DEVICE

Conventional dry ventilator circuit with HME filter

The nebulizer is placed between the filter and the endotracheal tube.

Trial Locations (1)

1200

Cliniques Universiataires Saint-Luc, Brussels

All Listed Sponsors
lead

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

OTHER

NCT03464175 - Influence of Respiratory Gases Conditioning on Aerosol Delivery During Invasive Ventilation | Biotech Hunter | Biotech Hunter