506
Participants
Start Date
April 8, 2018
Primary Completion Date
December 31, 2018
Study Completion Date
June 30, 2019
Tranexamic Acid
TXA (10mg/kg) solution for injection from the vial will be diluted with 100 - 200ml electrolyte solution such as Normal Saline, Ringers solution, dextrose/water for injection on the same day it is to be used (i.e. when anaesthetist notes the patient has been randomized to receive TXA). Intravenous administration should be at a rate of 100mg or fraction thereof over at least 1 minute - usually at least 5 minutes. Standard practice is to administer over 20 minutes. Administration is to be done at least 10 minutes prior to skin incision.
Oxytocin
5IU of oxytocin are administered intravenously slowly once the baby has been delivered at caesarean section.
Harare Central Hospital, Harare
Parirenyatwa Group of Hospitals, Harare
University of Zimbabwe
OTHER