116
Participants
Start Date
May 1, 2018
Primary Completion Date
September 26, 2018
Study Completion Date
October 8, 2018
VX-659/TEZ/IVA
Participants received VX-659/TEZ/IVA orally once daily in the morning.
TEZ/IVA
Participants received TEZ/IVA orally once daily in the morning.
IVA
Participants received IVA orally once daily in the evening.
Placebo
Participants received placebo matched TEZ/IVA orally once daily in the morning.
Placebo
Participants received placebo matched to VX-659/TEZ/IVA orally once daily in the morning.
Columbia University Medical Center, New York
Northwell Health, Long Island Jewish Medical Center, New Hyde Park
Albany Medical College, Albany
SUNY Upstate Medical University, Syracuse
Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh
The Johns Hopkins Hospital, Baltimore
University of Miami/Miller School of Medicine, Miami
University of Alabama at Birmingham, Birmingham
Vanderbilt University Medical Center, Nashville
University of Tennessee Medical Center-Adult Cystic Fibrosis Clinic, Knoxville
Children's Foundation Research Center/ Le Bonheur Children's Hospital, Memphis
Cincinnati Children's Hospital Medical Center, Cincinnati
Indiana Clinical Research Center, IU Health University Hospital, Indianapolis
Helen DeVos Children's Hospital CF Center, Grand Rapids
The University of Iowa Hospitals and Clinics, Iowa City
Sanford Research/ USD, Sioux Falls
Advocate Children's Hospital- Park Ridge/ North Suburban Pulmonary and Critical Care Consultants, Niles
Washington University School of Medicine / St. Louis Children's Hospital, St Louis
Children's Mercy Hospital, Kansas City
Respiratory Diseases of Children and Adolescents, Oklahoma City
Baylor College of Medicine, Houston
St. Luke's CF Center of Idaho, Boise
University of Utah/ Primary Children's Medical Center, Salt Lake City
Oregon Health & Science University, Portland
Seattle Children's Hospital, Seattle
Yale New Haven Medical Center, New Haven
Boston Children's Hospital, Boston
Rutgers-Robert Wood Johnson Medical School, New Brunswick
The Alfred Hospital, Melbourne
Royal Adelaide Hospital, Adelaide
Prince Charles Hospital, Chermside
Institute for Respiratory Health Inc./ Sir Charles Gairdner Hospital, Nedlands
John Hunter Hospital & Hunter Medical Research Institute, New Lambton Heights
Charite Paediatric Pulmonology Department, Berlin
Pneumologische Praxis Pasing, München
Cork University Hospital, Dublin
Our Lady's Children's Hospital, Dublin
St. Vincent's University Hospital, Dublin
Hospital Universitari Vall d Hebron, Barcelona
Hospital Universitari Vall d'Hebron Servicio de Broncoscopia, Barcelona
Hospital Universitario Virgen del Rocio, Seville
Papworth Hospital NHS Foundation Trust, Papworth Everard, Cambridge
Liverpool Heart and Chest Hospital, Liverpool
Royal Brompton & Harefield NHS Foundation Trust, Royal Brompton Hospital, London
Wythenshawe Hospital, Manchester
University Hospital Llandough, Penarth
Vertex Pharmaceuticals Incorporated
INDUSTRY