14
Participants
Start Date
February 12, 2018
Primary Completion Date
June 11, 2018
Study Completion Date
June 11, 2018
Euglycaemic Clamp
All 14 subjects will undergo an euglycaemic clamp at Visit 2 with a plasma Glucose target of 5.5 mmol/L +/- 10% (4 timepoints for platelet activity parameter blood sampling)
Hyperinsulinaemic/Hypoglycaemic Clamp
All 14 subjects will undergo a hypoglycaemic/hyperinsulinaemic clamp at Visit 3 with 4 timepoints for platelet activity Parameter blood sampling 30 minutes after reaching certain plasma glucose plateaus (5.5 mmol/L; 3.5 mmol/L; 2.5 mmol/L; after recovery again at 5.5 mmol/L)
Medical University of Graz, Department for Internal Medicine, Graz
Merck Sharp & Dohme LLC
INDUSTRY
Medical University of Graz
OTHER