Effect of Different Types of Anesthesia on Perioperative Brain Natriuretic Peptide Levels in Parturient Cardiac Patient Undergoing Elective Cesarean Section

CompletedOBSERVATIONAL
Enrollment

60

Participants

Timeline

Start Date

February 18, 2018

Primary Completion Date

June 5, 2018

Study Completion Date

June 10, 2018

Conditions
General Anesthesia Versus Spinal Anesthesia on BNP Hormone Levels Preoperatively and Postoperatively in Parturient Cardiac Patient Undergoing C.S
Interventions
DIAGNOSTIC_TEST

G.A Group A:

"G.A will be conducted After pre-oxygenation for 3-5 minutes. thiopental (5 mg/kg) will be administered I.V, followed by succinylcholine 1.5 mg/kg. After tracheal intubation, the patients will be ventilated with 100% oxygen. isoflurane 0.8% will be added, to maintain the anesthesia. Further neuromuscular block will be maintained by using atracurium . After delivery of the fetus, fentanyl IV will be given 1ug/kg as analgesia and 20 IU oxytocin will be given by I.V infusion .Reverse neuromuscular blockade as necessary at completion of surgery. Extubate when the patient is awake~In the sitting position and after complete asepsis , 2-3 ml of Lidocaine will be injected subcutaneously, spinal anesthesia will be performed at interspace L3-4 or L4-5, midline approaches using 22 guage Quinke needle . 2.5 ml of hyperbaric bupivacaine 0.5% in addition to 25 μg fentanyl will be injected into the subarachnoid space after successful dural puncture and confirmation by barbotage."

Trial Locations (1)

1

Cairo University, Cairo

All Listed Sponsors
collaborator

Mohamed, Ahmed A., M.D.

INDIV

collaborator

Sahr Marzouk

UNKNOWN

collaborator

Heba Omar

UNKNOWN

collaborator

Michael Wahib Wadeed

UNKNOWN

lead

Cairo University

OTHER

NCT03460184 - Effect of Different Types of Anesthesia on Perioperative Brain Natriuretic Peptide Levels in Parturient Cardiac Patient Undergoing Elective Cesarean Section | Biotech Hunter | Biotech Hunter