Safety and Efficacy of Intrathecally Administered Magnesium Sulfate

NACompletedINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

January 1, 2018

Primary Completion Date

May 1, 2019

Study Completion Date

June 1, 2019

Conditions
Abdominal CancerAbdominal Pain
Interventions
PROCEDURE

intrathecal morphine+LA

Lumbar puncture will be performed in the sitting position. A 25 gauge (pencil point, Braun, Melsungen, Germany) spinal needle will be introduced into the subarachnoid space at the L3-L4 lumber level midline approach with the needle orifice cephalad. Cerebrospinal fluid will be aspirated and the ready mixture will be injected to subarachnoid space over the period of 15 s, with barbotage. patients will receive intrathecal LA 15 mg (3 mL) (hyperbaric bupivacaine 0.5%) intrathecal with 0.5 mg preservative free morphine + magnesium sulfate 100 mg.

PROCEDURE

intrathecal morphine+LA+ Mg sulp. 50

Lumbar puncture will be performed in the sitting position. A 25 gauge (pencil point, Braun, Melsungen, Germany) spinal needle will be introduced into the subarachnoid space at the L3-L4 lumber level midline approach with the needle orifice cephalad. Cerebrospinal fluid will be aspirated and the ready mixture will be injected to subarachnoid space over the period of 15 s, with barbotage.patients will receive intrathecal 15 mg (3 mL) of hyperbaric bupivacaine 0.5% intrathecal +0.5 mg preservative free morphine + magnesium sulphate 50 mg.

PROCEDURE

intrathecal morphine+LA+ Mg sulp. 100

Lumbar puncture will be performed in the sitting position. A 25 gauge (pencil point, Braun, Melsungen, Germany) spinal needle will be introduced into the subarachnoid space at the L3-L4 lumber level midline approach with the needle orifice cephalad. Cerebrospinal fluid will be aspirated and the ready mixture will be injected to subarachnoid space over the period of 15 s, with barbotage.patients will receive intrathecal 15 mg (3 mL) of hyperbaric bupivacaine 0.5% intrathecal with 0.5 mg preservative free morphine + magnesium sulphate 100 mg.

Trial Locations (1)

0020

South Egypt Cancer Institute, Assiut University, Arab Republic of Egypt, Asyut

All Listed Sponsors
lead

South Egypt Cancer Institute

OTHER

NCT03459417 - Safety and Efficacy of Intrathecally Administered Magnesium Sulfate | Biotech Hunter | Biotech Hunter