Evaluating Implementation Strategies to Scale-up Transdiagnostic Evidence-based Mental Health Care in Zambia

NACompletedINTERVENTIONAL
Enrollment

456

Participants

Timeline

Start Date

February 25, 2020

Primary Completion Date

October 31, 2023

Study Completion Date

February 29, 2024

Conditions
DepressionPost-traumatic Stress DisorderAnxietySubstance Abuse
Interventions
BEHAVIORAL

In-person CETA

The Common Elements Treatment Approach (CETA) is a transdiagnostic, multi-problem intervention designed to address adult and youth trauma, depression, anxiety, safety, and substance use. It is comprised of a small set of common elements found to be efficacious and prevalent across a range of EBTs to treat common mental health problems. CETA was designed to be flexible in the elements utilized, their order, and their dose (number of sessions) to allow counselors to address heterogeneity, comorbidity, and symptom fluctuations in and across clients. Treatment typically consists of 6 to 12 weekly, approximately 60-minute sessions delivered by lay workers.

BEHAVIORAL

Telephone CETA

"For adaptation of the CETA manual for telephone delivery, the Applied Mental Health Research (AMHR) Group at Johns Hopkins University (JHU) reviewed evidence-based telehealth strategies and recommendations, telehealth ethical and legal guidelines, and clinical recommendations from telehealth providers. In addition, local TTTs in multiple contexts reviewed telehealth modifications and provided input that was incorporated into the final T-CETA manual used in this study. No changes were made to the structure, duration, and dose of CETA sessions, treatment components, or measurement-based clinical decision-making processes. Telehealth modifications, additions, and strategies were incorporated throughout the manual in delineated telehealth boxes. This way, the original manual was maintained outside of the telehealth boxes, allowing for clear identification and training of telehealth modifications for both new and existing CETA counselors."

BEHAVIORAL

Treatment as Usual (TAU)

The control condition is defined as 'treatment as usual'. In Zambia, there are no formal services or standard of care treatments for mental and behavioral health problems among AYA. There are, however, organizations (such as non-governmental organizations) operating in Lusaka that provide intermittent services for these types of problems. Some AYA receive informal counseling from parish priests or other leaders in their communities. In this study we are therefore defining these types of informal services as 'treatment-as-usual.' We will closely track the type, number, and degree of these kinds of services that all participants receive and access. Following the conclusion of the study, we will offer the CETA intervention to control participants if it has been found to be safe and effective

Trial Locations (1)

Unknown

Centre for Infectious Disease Research in Zambia, Lusaka

All Listed Sponsors
collaborator

Johns Hopkins University

OTHER

collaborator

University of Alabama at Birmingham

OTHER

collaborator

Education Development Center, Inc.

INDUSTRY

collaborator

Columbia University

OTHER

lead

Centre for Infectious Disease Research in Zambia

OTHER

NCT03458039 - Evaluating Implementation Strategies to Scale-up Transdiagnostic Evidence-based Mental Health Care in Zambia | Biotech Hunter | Biotech Hunter