Norepinephrine Infusion Versus Midodrine & Octreotide in Patients With Hepatorenal Syndrome Type 1.

PHASE4CompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

August 15, 2018

Primary Completion Date

April 20, 2020

Study Completion Date

July 10, 2020

Conditions
Renal Impairment in Hepatorenal Syndrome
Interventions
DRUG

norepinephrine versus midodrine & octreotide

either intravenous infusion (IVi) norepinephrine in a dose of 0.05-0.3ug/Kg/min. to keep mean arterial pressure ≥ 80-100mmHg \& continued either until HRS reversal or for maximum 10 days or oral midodrine 5mg three times/day \& can be increased every 24h up to 12.5mg three times daily plus octreotide 100ug/ 6h subcutaneous \& if needed increased to 200ug/6h.

Trial Locations (1)

Unknown

NHTMRI, Cairo

All Listed Sponsors
lead

National Hepatology & Tropical Medicine Research Institute

OTHER_GOV

NCT03455322 - Norepinephrine Infusion Versus Midodrine & Octreotide in Patients With Hepatorenal Syndrome Type 1. | Biotech Hunter | Biotech Hunter