Mechanisms of Obesity and Its Metabolic Complications in Youth

NACompletedINTERVENTIONAL
Enrollment

38

Participants

Timeline

Start Date

August 18, 2018

Primary Completion Date

June 30, 2024

Study Completion Date

June 30, 2024

Conditions
Obesity, Childhood
Interventions
DIETARY_SUPPLEMENT

obese carbohydrate diet

The experimental diet will consist of 30% carbohydrates (CHO), 35% protein, and 35% fat. Since the experimental diet is lower in CHO, the fiber and sugar content will be calculated based on total CHO in the same percentage as the control (0.25 g fiber per each kcal of CHO and 18.2% sugar for total CHO).

DIETARY_SUPPLEMENT

lean carbohydrate diet

The control diet composition will follow the American Dietary Guidelines of 55% carbohydrates (CHO), 15% protein, and 30% fat. CHO content will be primarily complex CHO of high quality (14 g fiber/1,000 kcals and \<10% of total kcals in the form of sugar).

Trial Locations (1)

06520

Hospital Research Unit, New Haven

All Listed Sponsors
collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

lead

Yale University

OTHER

NCT03454828 - Mechanisms of Obesity and Its Metabolic Complications in Youth | Biotech Hunter | Biotech Hunter