Efficacy and Safety of 0.25% Timolol Gel in Healing Surgical Open Wounds

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

88

Participants

Timeline

Start Date

August 20, 2018

Primary Completion Date

December 29, 2020

Study Completion Date

June 30, 2021

Conditions
Wound of SkinWound HealWound OpenSurgical Wound
Interventions
DRUG

0.25% Timolol gel with paraffin gauze dressings

Timolol 0.25% gel will be applied to wound bed immediately after surgery before dressing is applied. Starting the day after surgery: each day, the patient will cleanse the surgical site, apply 0.25% topical timolol gel (1 drop = 0.1ml for each cm2 of wound area), and re-cover wound with clean dressing

OTHER

Vaseline dressing

Vaseline will be applied to wound bed immediately after surgery before dressing is applied. Starting the day after surgery: each day, the patient will cleanse the surgical site, apply Vaseline, and re-cover wound with clean dressing

Trial Locations (1)

02130

Mohs and Dermatologic Surgery Center, Brigham and Women's Hospital, Boston

All Listed Sponsors
lead

Brigham and Women's Hospital

OTHER

NCT03452072 - Efficacy and Safety of 0.25% Timolol Gel in Healing Surgical Open Wounds | Biotech Hunter | Biotech Hunter