2,000
Participants
Start Date
January 23, 2018
Primary Completion Date
June 30, 2021
Study Completion Date
June 30, 2021
antipsychotic medications
olanzapine, risperidone, aripiprazole, amisulpride, ziprasidone, and haloperidol groups
adjunctive group
antipsychotic plus placebo, antipsychotic plus sulforaphane(3 tables per day, consisting of 30 mg of SFN-glucosinolate per day), and antipsychotic plus minocycline(200mg per day) groups.
metformin and lifestyle intervention
different dose metformin combines lifestyle intervention
Mental Health Institute of 2nd Xiangya Hospital,CSU, Changsha
Xiangya Hospital of Central South University
OTHER
Shanghai Mental Health Center
OTHER
West China Hospital
OTHER
First Affiliated Hospital of Zhejiang University
OTHER
Air Force Military Medical University, China
OTHER
Jiangsu Province Nanjing Brain Hospital
OTHER
First Affiliated Hospital of Harbin Medical University
OTHER
Shanxi Medical University
OTHER
First Affiliated Hospital of Kunming Medical University
OTHER
Guangzhou Mental Hospital
OTHER
First Affiliated Hospital of Chongqing Medical University
OTHER
Capital Medical University
OTHER
China Medical University, China
OTHER
The First Affiliated Hospital of Zhengzhou University
OTHER
First Affiliated Hospital Xi'an Jiaotong University
OTHER
Hebei Medical University
OTHER
Shenzhen Mental Health Center
OTHER
Sun Yat-sen University
OTHER
Wuhan Mental Health Centre
OTHER
Shanghai Jiao Tong University School of Medicine
OTHER
Central South University
OTHER