19/5000 (SYNAPSOT21) Predictive Factors of Sleep Apnea Syndrome in Down Syndrome

CompletedOBSERVATIONAL
Enrollment

40

Participants

Timeline

Start Date

November 15, 2017

Primary Completion Date

July 11, 2019

Study Completion Date

July 11, 2019

Conditions
Down SyndromeSleep Apnea, ObstructivePolysomnography
Interventions
DIAGNOSTIC_TEST

Assessment of OSAS predictive factors

"All subjects of the two groups realized the same assessment:~* Anthropometric evaluation~* biological examination (hormonal, inflammatory and complete blood count, and lipidic profile)~* rest electrocardiogram~* motor assessment (strenght, flexibility and balance)~* actigraphy~* Autonomic nervous system assessment during sleep~* Autonomic nervous system assessment during head up tilt test before and after physical exercise~* maximal treadmill test (VO2 max measure)~* polysomnography~* seismocardiography~* questionnaires :sleep and physical activity"

Trial Locations (1)

38130

CHU Grenoble Alpes, Échirolles

All Listed Sponsors
lead

University Hospital, Grenoble

OTHER

NCT03445962 - 19/5000 (SYNAPSOT21) Predictive Factors of Sleep Apnea Syndrome in Down Syndrome | Biotech Hunter | Biotech Hunter