Efficacy of Metformin in Preventing Diabetes in China

PHASE4CompletedINTERVENTIONAL
Enrollment

1,724

Participants

Timeline

Start Date

April 25, 2017

Primary Completion Date

June 30, 2021

Study Completion Date

June 30, 2021

Conditions
PreDiabetes
Interventions
DRUG

metformin

Metformin tablets will be administrated in the experimental arm.

OTHER

Standard lifestyle intervention

"Standard lifestyle advice will be united for all subjects by providing special booklet.~* All participants will receive 20-30 minutes individual or group session with assigned nurse addressing the harm of prediabetes and the importance of a healthy lifestyle for preventing Diabetes.~* The amount of energy intake of the participants will be calculated based on the ideal body weight and physical activity levels. The sample recipe will be explained by the nurse and provided in the diet instruction.~* Moderate intensity physical activity (150 minutes per week) is recommended.~* Smoking cessation is encouraged for the smoker.~* Excessive alcohol intake is encouraged to avoid."

Trial Locations (1)

050000

The Second Hospital of Hebei Medical University, Shijiazhuang

All Listed Sponsors
lead

Chinese Association of Geriatric Research

OTHER

NCT03441750 - Efficacy of Metformin in Preventing Diabetes in China | Biotech Hunter | Biotech Hunter