Induction Study #1 of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease

PHASE3TerminatedINTERVENTIONAL
Enrollment

625

Participants

Timeline

Start Date

February 27, 2018

Primary Completion Date

October 1, 2024

Study Completion Date

October 1, 2024

Conditions
Crohn Disease
Interventions
DRUG

Ozanimod

Specified dose on specified days

OTHER

Placebo

Specified dose on specified days

Trial Locations (408)

0

Local Institution - 501, Buenos Aires

1090

Local Institution - 940, Brussels

1180

Local Institution - 494, Buenos Aires

1202

Local Institution - 747, Sofia

1527

Local Institution - 627, Sofia

1606

Local Institution - 749, Sofia

1702

Local Institution - 571, Buenos Aires

1784

Local Institution - 748, Sofia

2000

Local Institution - 496, Rosario

Local Institution - 497, Rosario

2139

Local Institution - 310, Concord

2200

Local Institution - 325, Bankstown

2400

Local Institution - 611, Copenhagen

2500

Local Institution - 323, Wollongong

2650

Local Institution - 939, Edegem

2700

Local Institution - 456, Blagoevgrad

2747

Local Institution - 319, Kingswood

2930

Local Institution - 943, Brasschaat

3000

Local Institution - 942, Leuven

3001

Local Institution - 967, Bern

3004

Local Institution - 709, Melbourne

3128

Local Institution - 330, Box Hill

3181

Local Institution - 427, Seoul

4000

Local Institution - 492, San Miguel de Tucumán

Local Institution - 936, Liège

4002

Local Institution - 746, Plovdiv

4100

Local Institution - 938, Seraing

4102

Local Institution - 311, Woolloongabba

4210

Local Institution - 562, Kyiv

4300

Local Institution - 610, Holbæk

4558

Local Institution - 707, Maroochydore

4800

Local Institution - 609, Nykøbing Falster

5000

Local Institution - 308, Adelaide

5011

Local Institution - 320, Woodville South

5112

Local Institution - 708, Adelaide

6000

Local Institution - 553, Stara Zagora

6150

Local Institution - 316, Murdoch

6700

Local Institution - 448, Mexico City

7500

Local Institution - 941, Tournai

7985

Local Institution - 439, Seoul

8091

Local Institution - 969, Zurich

9000

Local Institution - 937, Ghent

9002

Local Institution - 754, Varna

9007

Local Institution - 968, Sankt Gallen

10000

Local Institution - 452, Zagreb

Local Institution - 761, Zagreb

Local Institution - 762, Zagreb

Local Institution - 766, Zagreb

10021

Local Institution - 105, New York

10075

Local Institution - 043, New York

10117

Local Institution - 626, Berlin

10468

Advantage Clinical Trials, The Bronx

10825

Local Institution - 665, Berlin

Local Institution - 842, Bucharest

11000

Local Institution - 246, Belgrade

11021

Local Institution - 009, Great Neck

11235

Local Institution - 144, Brooklyn

11923

Local Institution - 435, Guri-si

12746

Local Institution - 536, Riyadh

13620

Local Institution - 436, Seongnam-si

13915

Local Institution - 646, Marseille

14000

Local Institution - 368, Prague

14021

Local Institution - 776, Prague

14050

Local Institution - 650, Berlin

14080

Local Institution - 530, Tlalpan

14127

Local Institution - 094, Orchard Park

14611

Local Institution - 535, Riyadh

16059

Local Institution - 360, Bursa

16803

Penn State University Milton S Hershey Medical Center, State College

17033

Local Institution - 197, Hershey

20089

Local Institution - 672, Milan

20110

Local Institution - 298, Manassas

20122

Local Institution - 686, Milan

20132

Local Institution - 334, Milan

20155

Local Institution - 189, Gainesville

20246

Local Institution - 659, Hamburg

20900

Local Institution - 678, Monza

21018

Local Institution - 224, Vinnytsia

Local Institution - 971, Vinnytsia

21061

Local Institution - 282, Glen Burnie

21079

Local Institution - 616, Dijon

21100

Local Institution - 670, Varese

21224

Local Institution - 278, Baltimore

21228

Local Institution - 129, Catonsville

22100

Local Institution - 344, Nahariya

22252

Local Institution - 537, Jeddah

23188

Local Institution - 296, Williamsburg

23434

Virginia Gastroenterology Institute PC, Suffolk

23805

Local Institution - 139, Petersburg

25123

Local Institution - 684, Brescia

25124

Local Institution - 688, Brescia

27100

Local Institution - 673, Pavia

27612

Local Institution - 302, Raleigh

27834

Local Institution - 133, Greenville

28006

Local Institution - 691, Madrid

28046

Local Institution - 692, Madrid

28204

Local Institution - 152, Charlotte

28207

Local Institution - 055, Charlotte

28801

Local Institution - 017, Asheville

29425

Local Institution - 289, Charleston

30308

Local Institution - 205, Atlanta

30322

Local Institution - 222, Atlanta

30342

Local Institution - 019, Atlanta

Local Institution - 063, Atlanta

30460

Local Institution - 769, Pilsen

31000

Local Institution - 763, Osijek

31020

Local Institution - 528, Chihuahua City

31059

Local Institution - 643, Toulouse

31201

Local Institution - 028, Macon

31904

Local Institution - 074, Columbus

32127

Local Institution - 098, Port Orange

32168

Local Institution - 214, New Smyrna Beach

32253

Local Institution - 534, Dammam

32608

Local Institution - 218, Gainesville

32819

Local Institution - 076, Orlando

33010

Local Institution - 203, Hialeah

33016

Harmony Medical Research Institute, Hialeah

Local Institution - 078, Hialeah

33021

Local Institution - 179, Hollywood

33033

Local Institution - 101, Homestead

33100

Local Institution - 680, Udine

33125

Local Institution - 199, Miami

33126

LCC Medical Research Institute, LLC, Miami

33156

Local Institution - 169, Miami

33612

Local Institution - 226, Tampa

33614

Local Institution - 149, Tampa

33777

Local Institution - 016, Largo

34093

Local Institution - 362, Istanbul

34109

Local Institution - 090, Naples

34295

Local Institution - 507, Montpellier

34607

Local Institution - 114, Weeki Wachee

34840

Local Institution - 355, Istanbul

35033

Local Institution - 641, Rennes

35128

Local Institution - 685, Padua

36011

Local Institution - 905, Poltava

37024

Local Institution - 676, Verona

37211

Local Institution - 121, Nashville

37212

Vanderbilt University Medical Center, Nashville

38261

Advanced Gastroenterology, Union City

38320

Local Institution - 698, San Cristóbal de La Laguna

38700

Local Institution - 615, Grenoble

39216

Local Institution - 274, Jackson

40138

Local Institution - 677, Bologna

41009

Local Institution - 696, Seville

41013

Local Institution - 705, Seville

41380

Local Institution - 354, Izmit/Kocaeli

43005

Local Institution - 240, Lutsk

43401

Local Institution - 775, Most

44060

Local Institution - 177, Mentor

44122

Local Institution - 210, Beachwood

44195

Local Institution - 018, Cleveland

44483

Local Institution - 211, Warren

45030

Local Institution - 526, Zapapan

45219

Local Institution - 291, Cincinnati

46008

Local Institution - 934, Ternopil

48000

Local Institution - 453, Koprivnica

48034

Local Institution - 108, Southfield

48197

Local Institution - 300, Ypsilanti

48723

Local Institution - 191, Caro

49074

Local Institution - 950, Dnipropetrovsk

49201

Local Institution - 441, Busan

49519

Local Institution - 301, Wyoming

50325

Iowa Digestive Disease Center, Clive

51000

Local Institution - 764, Rijeka

52621

Local Institution - 342, Ramat Gan

53024

Aurora Health Care Aurora Research, Grafton

58001

Local Institution - 914, Chernivtsi

59037

Local Institution - 633, Lillie Cedex

60431

Local Institution - 662, Frankfurt

60594

Local Institution - 654, Frankfurt

60612

Local Institution - 194, Chicago

60622

Local Institution - 036, Chicago

61018

Local Institution - 919, Kharkiv

61080

Local Institution - 359, Trabzon

61801

Local Institution - 146, Urbana

63110

Local Institution - 029, St Louis

64610

Local Institution - 532, Monterrey

64718

Local Institution - 525, Monterrey

65025

Local Institution - 242, Odesa

66100

Local Institution - 687, Chieti

67000

Local Institution - 363, Kozlu

67067

Local Institution - 655, Ludwigshafen am Rhein

Local Institution - 730, Ludwigshafen am Rhein

70013

Local Institution - 689, Castellana Grotte

70125

Local Institution - 104, New Orleans

70360

CroNOLA LLC, Houma

70376

Local Institution - 661, Stuttgart

70601

Local Institution - 053, Lake Charles

71000

Local Institution - 738, Sarajevo

Local Institution - 742, Sarajevo

71434

Local Institution - 235, Szczecin

72076

Local Institution - 666, Tübingen

72117

Local Institution - 026, North Little Rock

73104

Local Institution - 208, Oklahoma City

73112

Local Institution - 131, Oklahoma City

75701

Local Institution - 073, Tyler

76008

Local Institution - 229, Ivano-Frankivsk

76018

Local Institution - 912, Ivano-Frankivsk

76031

Local Institution - 612, Rouen

76070

Local Institution - 529, Querétaro City

76092

Local Institution - 007, Southlake

76100

Local Institution - 338, Rehovot

77030

Local Institution - 056, Houston

Local Institution - 150, Houston

77043

Local Institution - 102, Houston

77070

Local Institution - 082, Houston

77074

Local Institution - 303, Houston

77084

Local Institution - 088, Houston

77900

Local Institution - 771, Olomouc

78000

Local Institution - 743, Banja Luka

78215

Local Institution - 085, San Antonio

78229

Local Institution - 223, San Antonio

78742

Local Institution - 158, Austin

79010

Local Institution - 234, Lviv

79059

Local Institution - 910, Lviv

80054

Local Institution - 638, Amiens

80228

Local Institution - 297, Lakewood

81756

Local Institution - 239, Sopot

84132

Local Institution - 025, Salt Lake City

85381

Holland Center for Family Health, Peoria

88000

Local Institution - 741, Mostar

88100

Local Institution - 679, Catanzaro

89081

Local Institution - 663, Ulm

90027

Local Institution - 061, Los Angeles

90067

Local Institution - 110, Los Angeles

90146

Local Institution - 682, Palermo

91031

Local Institution - 339, Jerusalem

91911

Local Institution - 165, Chula Vista

91942

San Diego Clinical Trials, La Mesa

92056

Alliance Clinical Research, Oceanside

92123

Local Institution - 003, San Diego

92377

Local Institution - 006, Rialto

92691

Local Institution - 140, Mission Viejo

92843

Local Institution - 039, Garden Grove

92868

Local Institution - 027, Orange

93012

Local Institution - 284, Camarillo

94010

Local Institution - 711, Créteil

94304

Palo Alto Center-Palo Alto Medical Foundation Research Institute, Palo Alto

97239

Local Institution - 113, Portland

98125

Local Institution - 674, Messina

99204

Local Institution - 125, Spokane

110002

Local Institution - 457, Delhi

110029

Local Institution - 411, New Delhi

111123

Local Institution - 851, Moscow

122002

Local Institution - 332, Gurgaon

141001

Local Institution - 446, Ludhiana

173008

Local Institution - 855, Veliky Novgorod

185019

Local Institution - 858, Petrozavodsk

194044

Local Institution - 862, Saint Petersburg

194354

Local Institution - 847, Saint Petersburg

195009

Local Institution - 857, Saint Petersburg

195067

Local Institution - 845, Saint Petersburg

195257

Local Institution - 856, Saint Petersburg

196603

Local Institution - 859, Pushkin

200642

Local Institution - 843, Craiova

210604

Local Institution - 737, Vitebsk

230026

Local Institution - 745, Grodno

300053

Local Institution - 806, Tula

302004

Local Institution - 443, Jaipur

302006

Local Institution - 399, Jaipur

344022

Local Institution - 883, Rostov-on-Don

357502

Local Institution - 960, Pyatigorsk

357538

Local Institution - 846, Pyatigorsk

395002

Local Institution - 407, Surat

400001

Local Institution - 838, Cluj-Napoca

420103

Local Institution - 892, Kazan'

443041

Local Institution - 844, Samara

450071

Local Institution - 861, Ufa

500032

Local Institution - 331, Hyderabad

500084

Local Institution - 444, Hyderabad

540136

Local Institution - 840, Târgu Mureş

600023

Local Institution - 935, Vladimir

628012

Local Institution - 599, Khanty-Mansiysk

630007

Local Institution - 594, Novosibirsk

641044

Local Institution - 408, Coimbatore

660037

Local Institution - 927, Krasnoyarsk

664049

Local Institution - 848, Irkutsk

672090

Local Institution - 598, Chita

682041

Local Institution - 445, Kochi

690091

Local Institution - 999, Vladivostok

690922

Local Institution - 986, Vladivostok

4070038

Local Institution - 389, Concepción

5962025

Local Institution - 345, Bat Yam

7500010

Local Institution - 392, Santiago

7500571

Local Institution - 387, Santiago

7550000

Local Institution - 391, Santiago

8320000

Local Institution - 390, Santiago

06010

Local Institution - 225, Bristol

06510

Local Institution - 091, New Haven

33756-3839

Local Institution - 062, Clearwater

40536-0298

Local Institution - 155, Lexington

02467

Local Institution - 142, Chestnut Hill

01655

Local Institution - 228, North Worcester

01199

Local Institution - 286, Springfield

07631

Local Institution - 215, Englewood

02904

Local Institution - 253, Providence

B1878

Local Institution - 500, Buenos Aires

X5003DCE

Local Institution - 570, Córdoba

X5016

Local Institution - 495, Córdoba

B7600

Local Institution - 569, Mar del Plata

S2002

Local Institution - 502, Rosario, Santa Fe

NSW 2050

Local Institution - 324, Sydney, NSW

T2N 4Z6

Local Institution - 273, Calgary

T5R 1W2

Local Institution - 227, Edmonton

V1Y 1Z9

Local Institution - 263, Kelowna

V5Z1M9

Local Institution - 255, Vancouver

R3CON2

Local Institution - 261, Winnipeg

B4V 3N2

Local Institution - 268, Bridgewater

N6A 5A5

Local Institution - 252, London

N6A 5W9

Local Institution - 251, London

M5G 1X8

Local Institution - 275, Toronto

L4L 4Y7

Local Institution - 271, Vaughan

HR-21000

Local Institution - 765, Split

615 00

Local Institution - 767, Brno

656 91

Local Institution - 772, Brno

500 12

Local Institution - 773, Hradec Králové

532 03

Local Institution - 774, Pardubice

120 00

Local Institution - 573, Prague

150 06

Local Institution - 768, Prague

190 00

Local Institution - 770, Prague

FI-20521

Local Institution - 614, Turku

0101

Local Institution - 248, Tbilisi

0112

Local Institution - 247, Tbilisi

0180

Local Institution - 249, Tbilisi

04103

Local Institution - 651, Leipzig

DO4 T6F4

Local Institution - 975, Dublin

D09 V2N0

Local Institution - 973, Dublin

00133

Local Institution - 681, Roma

00168

Local Institution - 675, Roma

00152

Local Institution - 671, Rome

LV-1002

Local Institution - 602, Riga

LV-1006

Local Institution - 601, Riga

LV-1038

Local Institution - 600, Riga

C.P 64000

Local Institution - 447, Monterrey

C.P 64060

Local Institution - 449, Monterrey

07020

Local Institution - 527, México

MD-2068

Local Institution - 811, Chisinau

MD2005

Local Institution - 810, Chisinau

MD2025

Local Institution - 809, Chisinau

Local Institution - 812, Chisinau

Local Institution - 813, Chisinau

22-400

Local Institution - 403, Zamość

Local Institution - 597, Zamość

15-276

Local Institution - 820, Bialystok

32-700

Local Institution - 818, Bochnia

40-040

Local Institution - 238, Katowice

40-660

Local Institution - 828, Katowice

40-752

Local Institution - 819, Katowice

30-363

Local Institution - 815, Krakow

31-156

Local Institution - 823, Krakow

31-501

Local Institution - 826, Krakow

57-300

Local Institution - 817, Kłodzko

90-302

Local Institution - 829, Lodz

91-839

Local Institution - 888, Lodz

20-049

Local Institution - 760, Lublin

10-561

Local Institution - 830, Olsztyn

45-819

Local Institution - 402, Opole

32-600

Local Institution - 400, Oświęcim

60-529

Local Institution - 758, Poznan

60-702

Local Institution - 575, Poznan

61-293

Local Institution - 401, Poznan

87-100

Local Institution - 822, Torun

43-100

Local Institution - 824, Tychy

90-447

Local Institution - 827, Ul. Piotrkowska 177

00-189

Local Institution - 410, Warsaw

01-192

Local Institution - 576, Warsaw

03-580

Local Institution - 825, Warsaw

04-501

Local Institution - 236, Warsaw

010719

Local Institution - 808, Bucharest

Local Institution - 836, Bucharest

013823

Local Institution - 499, Bucharest

021494

Local Institution - 795, Bucharest

022328

Local Institution - 837, Bucharest

050098

Local Institution - 839, Bucharest

11 000

Local Institution - 241, Belgrade

11 080

Local Institution - 245, Belgrade

152-703

Local Institution - 437, Ansan

06351

Local Institution - 433, Seoul

06591

Local Institution - 440, Seoul

120-752

Local Institution - 430, Seoul

138-736

Local Institution - 442, Seoul

03010

Local Institution - 703, Alicante

08916

Local Institution - 690, Badalona

08840

Local Institution - 700, Viladecans

06590

Local Institution - 356, Ankara

01030

Local Institution - 901, Kyiv

02000

Local Institution - 915, Kyiv

02002

Local Institution - 243, Kyiv

02175

Local Institution - 911, Kyiv

03037

Local Institution - 244, Kyiv

04053

Local Institution - 918, Kyiv

04107

Local Institution - 908, Kyiv

02029

Local Institution - 909, Vinnytsia

SO16 6YD

Local Institution - 723, Southampton

NW1 2BU

Local Institution - 729, London

B15 2SQ

Local Institution - 557, Birmingham

BS2 8HW

Local Institution - 714, Bristol

CF15 9SS

Local Institution - 560, Cardiff

PR7 7NA

Local Institution - 558, Chorley

NE46 1QJ

Local Institution - 559, Corbridge Road

BT16 1RH

Local Institution - 712, Dundonald

G51 4TF

Local Institution - 713, Glasgow

FY3 8NR

Local Institution - 716, Lancashire Blackpool

E1 1BB

Local Institution - 722, London

SE1 9RT

Local Institution - 715, London

M15 6SX

Local Institution - 561, North Manchester Science Park

SY38XQ

Local Institution - 593, Shrewsbury

TQ2 7AA

Local Institution - 718, Torquay

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Celgene

INDUSTRY

NCT03440372 - Induction Study #1 of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease | Biotech Hunter | Biotech Hunter