IMarkHD: in Vivo Longitudinal Imaging of HD Pathology

RecruitingOBSERVATIONAL
Enrollment

113

Participants

Timeline

Start Date

July 20, 2021

Primary Completion Date

June 30, 2027

Study Completion Date

June 30, 2027

Conditions
Huntington Disease
Interventions
RADIATION

PET imaging

"PET imaging Radiation: Radioligand \[¹¹C\]MePPEP Intravenous injection of radioligand in the arm with PET imaging of the brain. Radiation: Radioligand \[¹¹C\]IMA107 Intravenous injection of radioligand in the arm with PET imaging of the brain. Radiation: Radioligand \[¹¹C\]MDL100907 Intravenous injection of radioligand in the arm with PET imaging of the brain. Radiation: Radioligand \[¹¹C\]MDL100907 Intravenous injection of radioligand in the arm with PET imaging of the brain.~PET imaging Radiation: Radioligand \[¹¹C\]MePPEP Intravenous injection of radioligand in the arm with PET imaging of the brain. Radiation: Radioligand \[¹¹C\]IMA107 Intravenous injection of radioligand in the arm with PET imaging of the brain. Radiation: Radioligand \[¹¹C\]MDL100907 Intravenous injection of radioligand in the arm with PET imaging of the brain. Radiation: Radioligand \[¹¹C\]MDL100907 Intravenous injection of radioligand in the arm with PET imaging of the brain."

OTHER

Multi-modal MRI imaging

Multi-modal MRI imaging

Trial Locations (1)

SE5 8AF

RECRUITING

King's College London, London

All Listed Sponsors
collaborator

CHDI Foundation, Inc.

OTHER

lead

King's College London

OTHER