4,574
Participants
Start Date
March 3, 2018
Primary Completion Date
January 14, 2020
Study Completion Date
April 8, 2020
Tranexamic Acid Injectable Solution
After the routine and prophylactic administration of a uterotonic , the intervention will be the IV administration of a 10-ml blinded ampoule of the study drug (either TXA or placebo according to the randomisation sequence) to the woman within 3 minutes after birth, slowly (over 30-60 seconds), once the cord has been clamped.
Sodium Chloride 0.9%
After a routine and prophylactic administration of a uterotonic , the intervention will be the IV administration of a 10-ml blinded ampoule of the study drug (either TXA or placebo according to the randomisation sequence) to the patient within 3 minutes afterbirth), slowly (over 30-60 seconds), once the cord has been clamped.
Hôpital Saint Joseph Marseille, Marseille
Hopital Nord, Marseille
CHRU Côte de Nacre, Caen
CHU Jean Minjoz, Besançon
CHU Nîmes, Nîmes
Hôpital Paule de Viguier CHU Toulouse, Toulouse
CHU Bordeaux, Bordeaux
CHU de Montpellier, Montpellier
CHU Rennes, Rennes
CHU Tours, Tours
CHU Saint Etienne, Saint-Etienne
CHU Nantes, Nantes
CHU Angers, Angers
CHRU de Nancy, Nancy
CHU Estain, Clermont-Ferrand
CHU Strasbourg, Strasbourg
Hôpital Trousseau, Paris
Hôpital Saint Joseph Paris, Paris
Maternité de Port-Royal Paris, Paris
Hôpital universitaire Necker-Enfants malades, Paris
Hôpital universitaire Robert Debré, Paris
CHU Charles Nicolle, Rouen
Centre Hospitalier Intercommunal Poissy-Saint Germain, Poissy
Hôpital universitaire Kremlin-Bicètre, Paris
Centre Hospitalier Intercommunal de Créteil, Créteil
CH de Pau, Pau
Ministry of Health, France
OTHER_GOV
University Hospital, Bordeaux
OTHER