Effects of Noninvasive Ventilation Compared to Salbutamol

NACompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

June 10, 2017

Primary Completion Date

July 11, 2018

Study Completion Date

December 20, 2018

Conditions
Asthma
Interventions
DEVICE

Bilevel

Basal respiratory mechanics in spontaneous breathing will be analyzed by optoeletronic plethismography (OEP), followed by bronchial provocation with hypertonic saline solution 4.5%, another 45-second OEP uptake, IPAP 12 and EPAP 8 bilevel applied for 10 minutes, and a new uptake. All abstractions are preceded by a forced and slow spirometry maneuver. The entire procedure takes 1 hour.

DRUG

Albuterol

Basal respiratory mechanics in spontaneous breathing will be analyzed by optoeletronic plethismography (OEP), followed by bronchial provocation with hypertonic saline solution 4.5%, another 45-second OEP uptake, 400 micrograms inhaled Albuterol, and a new uptake. All abstractions are preceded by a forced and slow spirometry maneuver. The entire procedure takes 1 hour.

Trial Locations (1)

01.504-001

Nove de Julho University, São Paulo

All Listed Sponsors
lead

University of Nove de Julho

OTHER

NCT03430505 - Effects of Noninvasive Ventilation Compared to Salbutamol | Biotech Hunter | Biotech Hunter