Mesoglycan (Prisma®) Versus Placebo in Secondary Prevention of the Superficial Venous Thrombosis

PHASE2CompletedINTERVENTIONAL
Enrollment

560

Participants

Timeline

Start Date

March 26, 2018

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Superficial Venous Thrombosis of Leg, Secondary Prevention
Interventions
DRUG

Mesoglycan Oral Tablet

"Experimental drug: mesoglycan, already used in the treatment of chronic venous ulcers, is a complex mucopolysaccharide, composed of a mixture of glycosaminoglycans (mainly heparan-sulphate, dermatan sulfate), inhibitors of thrombin and of Factor Xa and active in restore flow-mediated vasodilation.~Used in oral formulation, hard capsules, 50 mg, twice-a-day, for 12 months. Reference therapy: placebo, organoleptically indistinguishable from the experimental drug, twice-a-day, for 12 months."

DRUG

Placebo Oral Tablet

Indistinguible placebo tablet

Trial Locations (1)

35138

Giuseppe Camporese, Padua

All Listed Sponsors
collaborator

Neopharmed Gentili S.p.A.

INDUSTRY

lead

Quovadis Associazione

OTHER

NCT03428711 - Mesoglycan (Prisma®) Versus Placebo in Secondary Prevention of the Superficial Venous Thrombosis | Biotech Hunter | Biotech Hunter